Monosodium phosphate
Drug ingredientCAS 7558-80-7
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$26M
Top sourceGermany 34%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 283522 · narrow
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 283522, which covers 6 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
DE 34%GermanyCN 27%ChinaMX 13%MexicoIT 10%ItalyCA 4%Canada
- Vietnam
- Denmark
- Poland
- Spain
- South Korea
- Brazil
- Czech Republic
- Finland
EPA-registered manufacturers (16)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Archroma Management Gmbh · CH Switzerland
Basf Se · DE Germany
Clariant International · CH Switzerland
Archroma U.S
Basf
Show all 16
Clariant
Condy Holdings
Ecolab
George S. Coyne Chemical
Hawkins
Henkel
Hydrite Chemical
Innophos Incorporated
Mount Vernon Mills
Nalco- An Ecolab
The Mosaic
Domestic parents -- activity not disclosed (7)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Basstech International
Budenheim Usa
Chemical Distribution Network
Harcros Chemicals
Icl Specialty Products North America
Show all 7
Target
Wego Chemical Group
EPA-registered importers (6)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Avantor
Lidochem
Prayon
Valudor Products
Wilbur-Ellis Holdings Ii
Show all 6
Wintersun International
Why It Matters
Sectors
HealthFoodEnergyWaterElectronicsTransportationMetals & MiningTextilesConsumer ProductsCore Chemicals
Downstream Uses
Appears in 6 drug and cosmetic product listings (FDA).
- •Saline Enema
- •Pedia-Lax
- •Fleet
- •Urogesic BLUE
- •Pure and Gentle Laxative
- •Relief
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 17 sectors as 16 functional roles.
- •pH regulating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (15%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Primary Metal Manufacturing (85%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Fabricated Metal Product Manufacturing (57%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Transportation Equipment Manufacturing (34%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Electrical Equipment, Appliance, and Component Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Computer and Electronic Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Machinery Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Fabricated Metal Product Manufacturing (24%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Computer and Electronic Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Transportation Equipment Manufacturing (25%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Electrical Equipment, Appliance, and Component Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Machinery Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Food, beverage, and tobacco product manufacturing (90%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Utilities (100%)Use—non-incorporative activities
- •Corrosion inhibitor in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (97%)Processing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Other (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Brightener in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Not Known or Reasonably Ascertainable
- •pH regulating agent in All Other Basic Inorganic Chemical Manufacturing (100%)Use—non-incorporative activities
- •Corrosion inhibitor in All Other Basic Organic Chemical Manufacturing (1%)Processing as a reactant
- •Anti-scaling agent in Utilities (99%)Processing as a reactant
- •CBI in CBICBI
- •Anti-scaling agent in All Other Basic Inorganic Chemical Manufacturing (1%)Processing as a reactant
- •Chelating agent in Fabricated Metal Product Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Binder in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Surface modifier in Fabricated Metal Product Manufacturing (29%)Processing—incorporation into article
- •Cleaning agent in Fabricated Metal Product Manufacturing (9%)Use—non-incorporative activities
- •Lubricating agent in Food, beverage, and tobacco product manufacturingUse—non-incorporative activities
- •Intermediate in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant
- •Anti-caking agent in Food, beverage, and tobacco product manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Food, beverage, and tobacco product manufacturing (97%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Food, beverage, and tobacco product manufacturing (3%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Thickening agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-scaling agent in Food, beverage, and tobacco product manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activitiesProcessing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Fabricated Metal Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Miscellaneous ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
Chemical Identity
CAS7558-80-7
PubChem CID23672064
DTXSIDDTXSID7035222
FormulaH2NaO4P
Mol. Weight119.977 g/mol
SMILESOP(=O)(O)[O-].[Na+]
Data Sources
- EPA CompTox (DSSTox) · DTXSID7035222Retrieved 2026-04-06
- PubChem · compound 23672064Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Monosodium phosphate (CAS 7558-80-7) https://chemicalindependence.com/chemical/7558-80-7/ EPA CompTox (DSSTox): DTXSID7035222. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7035222 PubChem: 23672064. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/23672064 EPA Chemical Data Reporting: 7558-80-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 7558-80-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 283522 for CAS 7558-80-7. Reporting year: 2024. https://usatrade.census.gov/