2,3,3,3-Tetrafluoropropene

CAS 754-12-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$94M

Top sourceChina 85%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290351 · narrow

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290351, which covers 4 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 85%ChinaMX 14%Mexico

Canada
United Kingdom
Vietnam

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Brainerd Chemical

Domestic parents -- activity not disclosed (2)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Chemours

Honeywell International (123312)

Why It Matters

Sectors

ElectronicsTransportationMetals & MiningCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 1 functional role.

•Refrigerants in Other (100%)Processing—repackaging
•Refrigerants in Electrical Equipment, Appliance, and Component Manufacturing (40%)Processing—repackaging
•Refrigerants in Transportation Equipment Manufacturing (40%)Use—non-incorporative activities
•Refrigerants in All Other Basic Inorganic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS754-12-1

PubChem CID2776731

DTXSIDDTXSID4074728

FormulaC3H2F4

Mol. Weight114.04 g/mol

SMILESC=C(C(F)(F)F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID4074728Retrieved 2026-04-06
PubChem · compound 2776731Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Electronics

Brief citations

2,3,3,3-Tetrafluoropropene (CAS 754-12-1) https://chemicalindependence.com/chemical/754-12-1/ EPA CompTox (DSSTox): DTXSID4074728. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4074728 PubChem: 2776731. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/2776731 EPA Chemical Data Reporting: 754-12-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 754-12-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290351 for CAS 754-12-1. Reporting year: 2024. https://usatrade.census.gov/