2-Hydroxy-2-methylpropanenitrile

CAS 75-86-5

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$281M

Top sourceChina 31%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292690 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

EPA-registered manufacturers (5)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Mitsubishi Chemical Group · JP Japan

Dow Chemical

Evonik

Ineos Us I

Mitsubishi Chemical America

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Bayer Ag · DE Germany

Bayer Us Holding

Why It Matters

Sectors

AgriculturePaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 2 functional roles.

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
•Dispersing agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$4.90/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$122.47 / 25 g

Purity99%

Vendors5 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

4 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$4.90	25 g	99%
Interbioscreen	Hong Kong	$41.00	10 g	95%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%

Chemical Identity

CAS75-86-5

PubChem CID6406

DTXSIDDTXSID7025427

FormulaC4H7NO

Mol. Weight85.1 g/mol

SMILESCC(C)(C#N)O

Data Sources

EPA CompTox (DSSTox) · DTXSID7025427Retrieved 2026-04-06
PubChem · compound 6406Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Hydroxy-2-methylpropanenitrile (CAS 75-86-5) https://chemicalindependence.com/chemical/75-86-5/ EPA CompTox (DSSTox): DTXSID7025427. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7025427 PubChem: 6406. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6406 EPA Chemical Data Reporting: 75-86-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 75-86-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292690 for CAS 75-86-5. Reporting year: 2024. https://usatrade.census.gov/