Trifluoromethane

CAS 75-46-7

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$2M

Top sourceChina 87%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 290341 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 87%ChinaJP 11%JapanTW 2%Taiwan

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Daikin America

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Chemours

EPA-registered importers (5)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

L'Air Liquide S A · FR France

Linde Plc · IE Ireland

Air Liquide Usa

Linde

Resonac America

Why It Matters

Sectors

EnergyElectronics

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Refrigerants in Industrial Gas Manufacturing (100%)Processing—repackaging
•Etching agent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities

Chemical Identity

CAS75-46-7

PubChem CID6373

DTXSIDDTXSID0026410

FormulaCHF3

Mol. Weight70.014 g/mol

SMILESC(F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID0026410Retrieved 2026-04-06
PubChem · compound 6373Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Trifluoromethane (CAS 75-46-7) https://chemicalindependence.com/chemical/75-46-7/ EPA CompTox (DSSTox): DTXSID0026410. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0026410 PubChem: 6373. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6373 EPA Chemical Data Reporting: 75-46-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 75-46-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290341 for CAS 75-46-7. Reporting year: 2024. https://usatrade.census.gov/