Acetyl chloride

CAS 75-36-5

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$384M

Top sourceMalaysia 21%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291590 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291590, which covers 588 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

MY 21%MalaysiaDE 13%GermanyNL 13%NetherlandsMX 10%MexicoIT 8%Italy

Singapore
Austria
United Kingdom
Philippines
Canada
Hungary
Turkey
Ukraine
Israel
Denmark
Czech Republic
Slovakia
Norway
Poland
Hong Kong
South Africa
Russia

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

The Chemical

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Pharmaceutical and Medicine ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.07/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$73.27 / 1 kg

Purity98%

Vendors6 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

5 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.07	1 kg	98%
Fluorochem UK	United Kingdom	$0.18	1 kg	98%
Fluorochem EU	Germany	$0.18	1 kg	98%
AK Scientific, Inc.	United States	$1.18	100 g	98%
Labotest KG	Germany	$217.80	5000 mg	90%

Chemical Identity

CAS75-36-5

PubChem CID6367

DTXSIDDTXSID2023852

FormulaC2H3ClO

Mol. Weight78.5 g/mol

SMILESCC(=O)Cl

Data Sources

EPA CompTox (DSSTox) · DTXSID2023852Retrieved 2026-04-06
PubChem · compound 6367Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Acetyl chloride (CAS 75-36-5) https://chemicalindependence.com/chemical/75-36-5/ EPA CompTox (DSSTox): DTXSID2023852. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2023852 PubChem: 6367. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6367 EPA Chemical Data Reporting: 75-36-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 75-36-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291590 for CAS 75-36-5. Reporting year: 2024. https://usatrade.census.gov/