Isobutane
CAS 75-28-5
U.S. production volumes are classified as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$917M
Top sourceCanada 95%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 290110 · basket
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 290110, which covers 58 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CA 95%CanadaDE 2%GermanyBR 1%BrazilKR 1%South Korea
- China
- Spain
- Italy
- Japan
- Israel
- Malaysia
- United Kingdom
- Austria
- Portugal
- India
- Poland
- Netherlands
- Turkey
- Switzerland
- Belgium
- Greece
- Sweden
EPA-registered manufacturers (40)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Pdvsa Petroleos S A · VE Venezuela
Shell Plc · GB United Kingdom
Totalenergies Se · FR France
Aux Sable Liquid Products
Berkshire Hathaway
Show all 40
Big West Oil
Blue Racer Midstream
California Resources
Chevron
Chevron Phiillips Chemical
Deer Park Refining
Delek Us Holdings
Delta Air Lines
Energy Transfer
Energy Transfer Gc Mont Belvieu Fractionators
Enterprise Products Operating
Et Gathering And Processing
ExxonMobil
Formosa Plastics Corporation, U.S.A.
Hep Javelina
Hf Sinclair
Kinder Morgan
Marathon Petroleum
Marathon Petroleum Coporation
Mplx
Oneok
Pbf Holding
Pdv Holding
Phillips 66
Shell Petroleum
Superior Refining
Targa Resources
The Williams Companies
Totalenergies Holdings Usa
Tpc Group
Trafigura Commodities Marketing
Trafigura Trading
True Oil
Vertex Energy- Mobile Refinery
Xto Energy
Domestic parents -- activity not disclosed (7)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
BP
Koch Industries
Lambda Energy Resouces
Martinez Renewables
Plains All American Pipeline
Show all 7
Valero Energy
Wrb Refining
EPA-registered importers (13)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Pembina Pipeline · CA Canada
Reckitt Benckiser Group · GB United Kingdom
Calumet Specialty Products Partners
Gunvor Usa
Hilti
Show all 13
Pembina Midstream (Usa)
Reckitt Benckiser
S.C. Johnson & Son
Solenis
Spray Planet
Target
Tartan Oil
United Refining
Why It Matters
Sectors
AgricultureEnergyMetals & MiningPlastics & RubberConsumer ProductsCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 11 sectors as 9 functional roles.
- •Fuel agents in Petroleum Refineries (100%)Processing as a reactant
- •Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel in All other Petroleum and Coal Products Manufacturing (100%)Processing as a reactant
- •Intermediate in Petroleum Refineries (100%)Processing as a reactant
- •Fuel in Petroleum Refineries (100%)Processing—repackaging
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
- •Fuel in Wholesale and Retail TradeProcessing—repackaging
- •Fuel agents in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Wholesale and Retail Trade (100%)Use—non-incorporative activities
- •Fuel agents in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Wholesale and Retail Trade (10%)Processing—repackaging
- •Fuel in Petrochemical Manufacturing (50%)Processing—repackaging
- •Fuel in Industrial Gas Manufacturing (19%)Processing—repackaging
- •Chelating agent in Petrochemical Manufacturing (74%)Processing as a reactant
- •Abrasives in Agriculture, Forestry, Fishing and Hunting (50%)Processing—incorporation into formulation, mixture, or reaction product
- •CBI in CBICBI
- •Fuel agents in All other Petroleum and Coal Products Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Processing aids, specific to petroleum production in Other (70%)Processing—incorporation into formulation, mixture, or reaction product
- •Propellants, non-motive (blowing agents) in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Propellants, non-motive (blowing agents) in Plastics Material and Resin Manufacturing (4%)Use—non-incorporative activities
- •Propellants, non-motive (blowing agents) in Industrial Gas ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Industrial Gas ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Fuels and fuel additives in Petroleum Refineries (100%)Processing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.65/gSigma-Aldrich (Rush Stock)
CountryGermany
Pack$228.20 / 350 g
Purity99%
Vendors2 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
1 more vendor
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Sigma-Aldrich | Germany | $0.65 | 350 g | 99% |
Chemical Identity
CAS75-28-5
PubChem CID6360
DTXSIDDTXSID1026401
FormulaC4H10
Mol. Weight58.12 g/mol
SMILESCC(C)C
Data Sources
- EPA CompTox (DSSTox) · DTXSID1026401Retrieved 2026-04-06
- PubChem · compound 6360Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Isobutane (CAS 75-28-5) https://chemicalindependence.com/chemical/75-28-5/ EPA CompTox (DSSTox): DTXSID1026401. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1026401 PubChem: 6360. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6360 EPA Chemical Data Reporting: 75-28-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 75-28-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290110 for CAS 75-28-5. Reporting year: 2024. https://usatrade.census.gov/