Ethylene oxide

CAS 75-21-8

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$72K

Top sourceTurkey 54%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 291010 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

TR 54%TurkeyCR 35%Costa RicaIN 7%IndiaJP 3%Japan

EPA-registered manufacturers (10)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Indorama Netherlands Bv · NL Netherlands

Sasol · ZA South Africa

Basf

Dow Chemical

Show all 10

Indorama Ventures Usa Holdings

Lotte Chemical Usa

Lyondell Chemical

Sasol Chemicals (Usa)

Shell Petroleum

Domestic parents -- activity not disclosed (2)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Eastman Chemical

Nalco- An Ecolab

Why It Matters

Sectors

EnergyConsumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 6 sectors as 2 functional roles.

•Intermediate in Petrochemical Manufacturing (100%)Processing as a reactant
•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
•Monomers in All Other Basic Inorganic Chemical ManufacturingUse—non-incorporative activities
•Monomers in All Other Chemical Product and Preparation ManufacturingUse—non-incorporative activities
•Monomers in All Other Basic Organic Chemical ManufacturingUse—non-incorporative activities
•Intermediate in Oil and Gas Drilling, Extraction, and Support activitiesProcessing as a reactant
•Intermediate in Wholesale and Retail TradeUse—non-incorporative activities
•Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS75-21-8

PubChem CID6354

DTXSIDDTXSID0020600

FormulaC2H4O

Mol. Weight44.05 g/mol

SMILESC1CO1

Data Sources

EPA CompTox (DSSTox) · DTXSID0020600Retrieved 2026-04-06
PubChem · compound 6354Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Ethylene oxide (CAS 75-21-8) https://chemicalindependence.com/chemical/75-21-8/ EPA CompTox (DSSTox): DTXSID0020600. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0020600 PubChem: 6354. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6354 EPA Chemical Data Reporting: 75-21-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 75-21-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291010 for CAS 75-21-8. Reporting year: 2024. https://usatrade.census.gov/