Difluoromethane

CAS 75-10-5

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$27M

Top sourceUnited Arab Emirates 50%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 290342 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

AE 50%United Arab EmiratesIN 46%IndiaCN 4%China

Canada

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Arkema

Domestic parents -- activity not disclosed (6)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Brainerd Chemical

Chemours

Fci

Honeywell International (123312)

Igas Holdings

Show all 6

Mexichem Fluor

EPA-registered importers (6)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Arkema · FR France

Harp Overseas Holdings · GB United Kingdom

A-Gas

Freskoa Usa

Harp Usa

Show all 6

Icool Usa Incorporated

Why It Matters

Sectors

EnergyElectronicsMetals & MiningConsumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 7 sectors as 1 functional role.

•Refrigerants in Other (100%)Processing—repackaging
•Refrigerants in Industrial Gas ManufacturingProcessing—repackaging
•Refrigerants in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Refrigerants in Electrical Equipment, Appliance, and Component Manufacturing (100%)Processing—incorporation into article
•Refrigerants in Wholesale and Retail TradeUse—non-incorporative activities
•Refrigerants in Miscellaneous ManufacturingProcessing—incorporation into article
•Refrigerants in Not Known or Reasonably Ascertainable (100%)Not Known or Reasonably Ascertainable

Chemical Identity

CAS75-10-5

PubChem CID6345

DTXSIDDTXSID6029597

FormulaCH2F2

Mol. Weight52.023 g/mol

SMILESC(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID6029597Retrieved 2026-04-06
PubChem · compound 6345Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Difluoromethane (CAS 75-10-5) https://chemicalindependence.com/chemical/75-10-5/ EPA CompTox (DSSTox): DTXSID6029597. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6029597 PubChem: 6345. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6345 EPA Chemical Data Reporting: 75-10-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 75-10-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290342 for CAS 75-10-5. Reporting year: 2024. https://usatrade.census.gov/