Argatroban

Drug ingredient

CAS 74863-84-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

17 FDA-registered drug labelers

Accord Healthcare Inc.

Amneal Pharmaceuticals LLC

Apothecon Pharmaceuticals Pvt Ltd

BrightGene Bio-Medical Technology Co., Ltd.

Caplin Steriles Limited

Curia Italy S.r.l.

Emcure Pharmaceuticals Limited

Eugia US LLC

Fresenius Kabi USA, LLC

Gland Pharma Limited

Hikma Pharmaceuticals USA Inc.

Lundbeck Pharmaceuticals Italy S.p.A.

Mullan Pharmaceutical Inc.

Mylan Institutional LLC

Par Health USA, LLC

Sagent Pharmaceuticals

Tianjin Weijie Pharmaceutical Co. Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Argatroban

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS74863-84-6

PubChem CID92722

DTXSIDDTXSID7046467

FormulaC23H36N6O5S

Mol. Weight508.6 g/mol

SMILESCC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C

Data Sources

PubChem · compound 92722Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Argatroban (CAS 74863-84-6) https://chemicalindependence.com/chemical/74863-84-6/ PubChem: 92722. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/92722 FDA National Drug Code directory: CAS 74863-84-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 74863-84-6. Reporting year: 2024. https://usatrade.census.gov/