Zinc sulfate heptahydrate

Drug ingredient

CAS 7446-20-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 7446-20-0 — 7 H₂O · 1 Zn²⁺

US production237.1K lb

Import value, 2024$179M

Import volume157.4K lb

Import dependency40%

Top sourceMexico 46%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 283329 · basket

EPA reports by year

2023: US production 237.1K lb · Imports 157.4K lb
2019: US production 448.4K lb · Imports Zero

These shares come from HS customs code 283329, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

MX 46%MexicoCN 19%ChinaCA 11%CanadaIN 9%IndiaFI 4%Finland

Italy
South Africa
Colombia
United Kingdom
Peru
Czech Republic
Taiwan
Hong Kong
Sweden
Belgium
Singapore
Netherlands
Hungary
Switzerland

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Bekaert

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Ch Biotech R&D · TW Taiwan

Ch Biotech

13 FDA-registered drug labelers

American Regent, Inc.

Avantor Performance Materials International, LLC

BioActive Nutritional, Inc.

Biophore India Pharmaceuticals Pvt. Ltd

Boiron

Hahnemann Laboratories, INC.

Jost Chemical Co

Macco Organiques, S.R.O.

Maithri Drugs Private Limited

METROCHEM API PRIVATE LIMITED

PEKANA Naturheilmittel GmbH

Professional Compounding Centers of America

Spectrum Laboratory Products, Inc.

Why It Matters

Sectors

HealthAgricultureTextiles

Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

•Zincum Sulphuricum
•Prostatone
•Multitrace-5
•Glucorekt
•Melatonin Forte
•Multitrace -4 Pediatric

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (100%)Processing—incorporation into formulation, mixture, or reaction product
•Plating agent in Textiles, apparel, and leather manufacturing (100%)Processing as a reactant

Chemical Identity

CAS7446-20-0

PubChem CID62640

DTXSIDDTXSID0040175

FormulaH14O11SZn

Mol. Weight287.6 g/mol

SMILESO.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[Zn+2]

Data Sources

EPA CompTox (DSSTox) · DTXSID0040175Retrieved 2026-04-06
PubChem · compound 62640Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Zinc sulfate heptahydrate (CAS 7446-20-0) https://chemicalindependence.com/chemical/7446-20-0/ EPA CompTox (DSSTox): DTXSID0040175. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0040175 PubChem: 62640. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/62640 EPA Chemical Data Reporting: 7446-20-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 7446-20-0. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 283329 for CAS 7446-20-0. Reporting year: 2024. https://usatrade.census.gov/