methotrexate sodium
Drug ingredientActive ShortageThis drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
Where It Comes From
27 FDA-registered drug labelers
A-S Medication Solutions
Accord Healthcare Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Aurobindo Pharma Limited
Bryant Ranch Prepack
Chartwell RX, LLC
Coupler LLC
Elite Laboratories, Inc.
Eugia US LLC
Excella GmbH & Co. KG
Fermion Oy
Fresenius Kabi USA, LLC
Golden State Medical Supply, Inc.
Hikma Pharmaceuticals USA Inc.
Hospira, Inc.
Medexus Pharma Inc.
MSN Laboratories Private Limited
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
NuCare Pharmaceuticals, Inc.
Proficient Rx LP
Safecor Health LLC
Sun Pharmaceutical Industries, Inc.
Teva Parenteral Medicines, Inc.
Teva Pharmaceuticals USA, Inc.
Teva Women's Health, Inc.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 4 drug and cosmetic product listings (FDA).
- •Methotrexate Sodium
- •Methotrexate
- •Rasuvo
- •Trexall
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
Active Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
current
Methotrexate Sodium Injection
03/13/2023Limited Availability
current
Methotrexate Sodium Injection
03/13/2023Available
current
Methotrexate Sodium Injection
03/13/2023Unavailable
Chemical Identity
CAS7413-34-5
PubChem CID11329481
DTXSIDDTXSID3037123
FormulaC20H20N8Na2O5
Mol. Weight498.4 g/mol
SMILESCN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
Data Sources
113294812026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/methotrexate sodium/cids/JSON
Archive: data/sources/pubchem_name/methotrexate sodium.json
CAS 7413-34-52026-04-25
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json
CAS 7413-34-52026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json