Ketorolac tromethamine
Drug ingredientActive ShortageCAS 74103-07-4
This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
US productionNot reported
Top sourceNo public record
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownWhere It Comes From
EPA and Census publish no US supply data for this chemical.
74 FDA-registered drug labelers
A-S Medication Solutions
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Allergan, Inc.
American Health Packaging
Amici Pharma Inc.
Apotex Corp.
ASCLEMED USA INC.
ATNAHS PHARMA US LIMITED
Aurobindo Pharma Limited
Baxter Healthcare Corporation
Bionpharma Inc.
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Caplin Steriles Limited
Cardinal Health 107, LLC
Chartwell RX, LLC
Chromo Laboratories India Private Limited
Civica, Inc.
Direct Rx
DR. REDDY'S LABORATORIES, INC.
Dr.Reddy's Laboratories Limited
Eugia US LLC
Fagron Inc
FOSUN PHARMA USA INC
Fresenius Kabi USA, LLC
Gland Pharma Limited
GLENMARK PHARMACEUTICALS INC., USA
Golden State Medical Supply, Inc.
Henry Schein, Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
Hospira, Inc.
Jubilant HollisterStier LLC
Leading Pharma, LLC
LETCO MEDICAL, LLC
Major Pharmaceuticals
Medical Purchasing Solutions, LLC
Medisca Inc.
Micro Labs Limited
MSN Laboratories Private Limited
Mylan Pharmaceuticals Inc.
Nephron Pharmaceuticals Corporation
NorthStar Rx LLC
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
Onesource Specialty Pharma Limited
Pacific Pharma, Inc.
PD-Rx Pharmaceuticals, Inc.
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
ProPharma Distribution
Quimica Sintetica S.A.
RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA
Redpharm Drug
REMEDYREPACK INC.
Sagent Pharmaceuticals
Sandoz Inc
SCL Lifesciences Limited
SOLA Pharmaceuticals, LLC
Spectrum Laboratory Products, Inc.
Sportpharm LLC
Sportpharm, Inc. dba Sportpharm
ST. MARY'S MEDICAL PARK PHARMACY
Sun Pharmaceutical Industries, Inc.
Symed Labs Limited
Teva Pharmaceuticals USA, Inc.
Vasudha Pharma Chem Limited
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.
Zyla Life Sciences US LLC
Why It Matters
Sectors
Health
Downstream Uses
Appears in 7 drug and cosmetic product listings (FDA).
- •ketorolac tromethamine
- •Toronova II SUIK
- •Toronova SUIK
- •Sprix
- •Acuvail
- •Acular
- •Acular LS
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
Active Shortage
Shortage History
Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.
- Current shortage
Ketorolac Tromethamine Injection
Shortage listed since March 23, 2018
Manufacturer reports: 3 unavailable, 1 limited, 3 available
- to be discontinued
Ketorolac Tromethamine Tablet
Shortage listed since April 20, 2026
Vendor Pricing
$3.84/gA2B Chem LLC
CountryUnited States
Pack$96.00 / 25 g
Purity98%
Vendors22 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
21 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Combi-Blocks, Inc. | United States | $3.95 | 100 g | 97% |
| AA BLOCKS | United States | $4.46 | 100 g | 98% |
| Aaron Chemicals LLC | Hong Kong | $5.29 | 100 g | 98% |
| Ambeed, Inc. | United States | $5.40 | 25 g | 98% |
| AK Scientific Specialized | United States | $5.48 | 25 g | 95% |
| Angene Chemical | China → Hong Kong | $5.66 | 100 g | 98% |
| AK Scientific, Inc. | United States | $7.36 | 25 g | 98% |
| Fulfilled by Molport | Latvia | $11.00 | 1 g | — |
| Life Chemicals Inc. | Ukraine → Canada | $21.00 | 1 g | 95% |
| MedChemExpress MCE | Sweden | $39.93 | 5 g | 99.53% |
| MedKoo Biosciences, Inc | United States | $58.00 | 25 g | 98% |
| Apexbio Technology LLC | United States | $63.00 | 1 g | 98.29% |
| Molnova | China | $71.00 | 1 g | 99% |
| AstaTech (2 weeks) | United States | $83.00 | 1 g | 98% |
| TargetMol Chemicals US | United States | $88.00 | 500 mg | 99.85% |
| Sigma-Aldrich (Rush Stock) | Germany | $148.98 | 1 g | 99% |
| Sigma-Aldrich | Germany | $148.98 | 1 g | 99% |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| Angene International Limited | United States | $1400.00 | 100 mg | 99% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
Chemical Identity
CAS74103-07-4
PubChem CID84003
DTXSIDDTXSID0045597
FormulaC19H24N2O6
Mol. Weight376.4 g/mol
SMILESC1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O
Data Sources
- PubChem · compound 84003Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA Drug ShortagesRetrieved 2026-10-04
Brief citations
Ketorolac tromethamine (CAS 74103-07-4) https://chemicalindependence.com/chemical/74103-07-4/ PubChem: 84003. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/84003 FDA National Drug Code directory: CAS 74103-07-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 74103-07-4. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/