hydrocortisone aceponate

Drug ingredient

CAS 74050-20-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 74050-20-7
US productionNot reported
Import value, 2024$154M
Top sourceItaly 60%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293729 · basket

These shares come from HS customs code 293729, which covers 57 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 60%ItalyES 14%SpainCN 11%ChinaDE 6%GermanyAT 2%Austria
2 FDA-registered drug labelers
Curia Spain S.A.U.
HOVIONE FARMACIENCIA SA

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS74050-20-7
PubChem CID68921
DTXSIDDTXSID50868278
FormulaC26H36O7
Mol. Weight460.6 g/mol
SMILESCCC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)COC(=O)C

Data Sources

Brief citations

hydrocortisone aceponate (CAS 74050-20-7) https://chemicalindependence.com/chemical/74050-20-7/ PubChem: 68921. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/68921 FDA National Drug Code directory: CAS 74050-20-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293729 for CAS 74050-20-7. Reporting year: 2024. https://usatrade.census.gov/