1-Propyne

CAS 74-99-7

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$246M

Top sourceCanada 51%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290129 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290129, which covers 108 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 51%CanadaZA 32%South AfricaBR 6%BrazilJP 4%JapanIT 1%Italy

Spain
Ireland
India
United Kingdom
Malaysia
Dominican Republic
Mexico
Switzerland
Australia
South Korea
Turkey
Portugal
Morocco
Guyana
Poland
Netherlands
Belgium
Slovakia
Ukraine

EPA-registered manufacturers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Shell Plc · GB United Kingdom

Basf

Shell Petroleum

Why It Matters

Sectors

Consumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$4.79/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$478.72 / 100 g

Purity99%

Vendors3 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

2 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$4.79	100 g	99%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS74-99-7

PubChem CID6335

DTXSIDDTXSID0026387

FormulaC3H4

Mol. Weight40.06 g/mol

SMILESCC#C

Data Sources

EPA CompTox (DSSTox) · DTXSID0026387Retrieved 2026-04-06
PubChem · compound 6335Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1-Propyne (CAS 74-99-7) https://chemicalindependence.com/chemical/74-99-7/ EPA CompTox (DSSTox): DTXSID0026387. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0026387 PubChem: 6335. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6335 EPA Chemical Data Reporting: 74-99-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 74-99-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290129 for CAS 74-99-7. Reporting year: 2024. https://usatrade.census.gov/