Hydrogen cyanide

Drug ingredient

CAS 74-90-8

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceNo public record

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 281112 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

EPA-registered manufacturers (8)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

China National Chemical · CN China

Ascend Performance Materials

Cornerstone Chemical

Dow Chemical

Evonik

Show all 8

Ineos Us I

Orica Usa

Syngenta Crop Protection

5 FDA-registered drug labelers

Boiron

DNA Labs, Inc.

OHM PHARMA INC.

Professional Complementary Health Formulas

Sandco International, Inc

Why It Matters

Sectors

Core ChemicalsHealthAgriculture

Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

•D-67
•Toxagent Detox 6035
•Hydrocyanicum acidum
•Joette Calabrese Survivalist Kit
•Musco MXT
•Cerebral Blood Stim Drops 2086

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 1 functional role.

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
•Intermediate in Petrochemical ManufacturingProcessing as a reactant
•Intermediate in All Other Basic Inorganic Chemical ManufacturingProcessing as a reactant
•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (91%)Processing as a reactant

Chemical Identity

CAS74-90-8

PubChem CID768

DTXSIDDTXSID9024148

FormulaCHN

Mol. Weight27.025 g/mol

SMILESC#N

Data Sources

EPA CompTox (DSSTox) · DTXSID9024148Retrieved 2026-04-06
PubChem · compound 768Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07

← Back to Dashboard ← Back to Core Chemicals

Brief citations

Hydrogen cyanide (CAS 74-90-8) https://chemicalindependence.com/chemical/74-90-8/ EPA CompTox (DSSTox): DTXSID9024148. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9024148 PubChem: 768. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/768 EPA Chemical Data Reporting: 74-90-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 74-90-8. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/