Methyl iodide

CAS 74-88-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$18M

Top sourceChina 42%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290369 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290369, which covers 96 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 42%ChinaIN 19%IndiaIT 14%ItalyIL 13%IsraelNL 9%Netherlands

Singapore
Germany
Hungary
Ukraine
Switzerland
Mexico
Hong Kong

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Toyota Tsusho · JP Japan

Deepwater Chemicals

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Iofina Chemical

Why It Matters

Sectors

HealthAgricultureCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 3 functional roles.

•Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (5%)Processing as a reactant
•Preservative in Agriculture, Forestry, Fishing and Hunting (5%)Processing as a reactant
•Catalyst in All Other Basic Organic Chemical Manufacturing (80%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.53/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$266.93 / 500 g

Purity99.5%

Vendors7 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

6 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.53	500 g	99.5%
Interbioscreen	Hong Kong	$24.00	10 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%

Chemical Identity

CAS74-88-4

PubChem CID6328

DTXSIDDTXSID0024187

FormulaCH3I

Mol. Weight141.939 g/mol

SMILESCI

Data Sources

EPA CompTox (DSSTox) · DTXSID0024187Retrieved 2026-04-06
PubChem · compound 6328Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methyl iodide (CAS 74-88-4) https://chemicalindependence.com/chemical/74-88-4/ EPA CompTox (DSSTox): DTXSID0024187. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0024187 PubChem: 6328. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6328 EPA Chemical Data Reporting: 74-88-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 74-88-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290369 for CAS 74-88-4. Reporting year: 2024. https://usatrade.census.gov/