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Methane

Drug ingredient

CAS 74-82-8

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI
Import value, 2024$114M
Top sourceCanada 67%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 271119, 271129 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 271119, 271129, which covers 118 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CA 67%CanadaCL 15%ChileKR 8%South KoreaIT 1%ItalyGB 1%United Kingdom
EPA-registered manufacturers (11)
Basf Se · DE Germany
Sasol · ZA South Africa
Shell Plc · GB United Kingdom
Basf
Dakota Gasification
Show all 11
Dow Chemical
Harvest Four Corners
Lyondell Chemical
Sasol Chemicals (Usa)
Shell
Shell Petroleum
Domestic parents -- activity not disclosed (3)
Aux Sable Liquid Products
BP
Formosa Plastics Corporation, U.S.A.
EPA-registered importers (1)
Gunvor Usa
1 FDA-registered drug labeler
Professional Complementary Health Formulas

Why It Matters

Sectors
HealthEnergyWaterPlastics & RubberConsumer ProductsCore Chemicals
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Toxagent Detox 6035
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 9 sectors as 4 functional roles.

  • •Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Fuel in All Other Chemical Product and Preparation Manufacturing (100%)Use—non-incorporative activities
  • •Fuel in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
  • •Fuel in UtilitiesUse—non-incorporative activities
  • •Fuel in Industrial Gas Manufacturing (100%)Processing as a reactant
  • •Fuel in Petroleum Refineries (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Plastics Product Manufacturing (100%)Processing—repackaging
  • •Monomers in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •X-ray absorber in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
  • •Fuel in Wholesale and Retail Trade (60%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS74-82-8
PubChem CID297
DTXSIDDTXSID8025545
FormulaCH4
Mol. Weight16.043 g/mol
SMILESC

Data Sources

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Brief citations

Methane (CAS 74-82-8) https://chemicalindependence.com/chemical/74-82-8/ EPA CompTox (DSSTox): DTXSID8025545. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8025545 PubChem: 297. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/297 EPA Chemical Data Reporting: 74-82-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 74-82-8. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 271119,271129 for CAS 74-82-8. Reporting year: 2024. https://usatrade.census.gov/