L-Arginine

Drug ingredient

CAS 74-79-3

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$240M

Top sourceChina 37%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292529 · basket

EPA reports by year

2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292529, which covers 64 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 37%ChinaDE 19%GermanyES 9%SpainIT 8%ItalyID 8%Indonesia

Switzerland
Canada
United Kingdom
Austria
Brazil
Israel
Australia
Hungary
Serbia
Denmark
Malaysia
Poland
Hong Kong
Ukraine
Singapore

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Avantor

Why It Matters

Sectors

Health

Downstream Uses

Appears in 40 drug and cosmetic product listings (FDA).

•Feelshion Glycolic Acid Exfoliating Face Pads
•Kidney Repair Center
•Aminosyn-PF
•Vascuflow
•Electrolyte Plus
•Strength F
•Vital II
•Plenamine

Show all 40

•Kabiven
•Clinimix
•Clinimix E
•Dr Dale Wellness NU Fem 1 2 3 All In One Topical Homeopathic
•Vital Female Sexual Energy
•N-17
•Clinisol
•CellTropin
•A L O Formula
•Adrenal and DHEA
•Strength M
•D-87
•ProSol
•TrophAmine
•TH-101
•Aminosyn II
•Metabatone
•Vital Skin Hair Nails
•OB Metab
•N-24
•Total PRO-JES
•Travasol
•Recovatone
•A-L-O Liquid Drops 2082
•Perikabiven
•Esokalli Delay Performance Gel
•BEE Venom SKIN Firming Cream
•L-Arginine High 7402
•Metab
•Growth Hormone Drops 2160
•L-Arginine 7401
•Premasol - sulfite-free (Amino Acid)

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS74-79-3

PubChem CID6322

DTXSIDDTXSID6041056

FormulaC6H14N4O2

Mol. Weight174.2 g/mol

SMILESC(CC(C(=O)O)N)CN=C(N)N

Data Sources

EPA CompTox (DSSTox) · DTXSID6041056Retrieved 2026-04-06
PubChem · compound 6322Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

L-Arginine (CAS 74-79-3) https://chemicalindependence.com/chemical/74-79-3/ EPA CompTox (DSSTox): DTXSID6041056. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6041056 PubChem: 6322. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6322 EPA Chemical Data Reporting: 74-79-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 74-79-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292529 for CAS 74-79-3. Reporting year: 2024. https://usatrade.census.gov/