(4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

Drug ingredient

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 7365-45-9
US ProductionCBI
Import Value$7.6B
Top SourceIreland 61%

The EPA did not publish how much of this chemical companies made or imported, or marked that amount confidential. Without that volume, ACID cannot calculate import dependency.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 18 chemicals in total. They estimate the bucket's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
EPA-registered importers (1)
Avantor

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • 15% azelaic acid acne cream
  • 10% azelaic acid acne cream
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.04/gAaron Chemicals LLC
CountryHong Kong
Pack$450.00 / 10 kg
Purity98%
Vendors28 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

27 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina Hong Kong$0.05500 g98%
AA BLOCKSUnited States$0.051 kg98%
A2B Chem LLCUnited States$0.051 kg98%
BLD Pharmatech GmbHGermany$0.061 kg97%
BLD Pharmatech Ltd.China$0.061 kg97%
ChemsceneUnited States$0.071 kg
Apollo Scientific USUnited Kingdom$0.091 kg99.5%
Fluorochem UKUnited Kingdom$0.111 kg97%
BLD Pharmatech Co., LimitedUnited States$0.111 kg97%
Ambeed, Inc.United States$0.111 kg97%
AK Scientific SpecializedUnited States$0.111 kg98%
Fluorochem EUGermany$0.13500 g97%
Angene International LimitedUnited States$0.14250 g98%
AK Scientific, Inc.United States$0.151 kg99%
Combi-Blocks, Inc.United States$0.251 kg97%
Sigma-Aldrich (Rush Stock)Germany$0.2950 kg99.5%
Sigma-AldrichGermany$0.2950 kg99.5%
AstaTech, IncUnited States$0.75100 g95%
Apexbio Technology LLCUnited States$0.96250 g98%
MedKoo Biosciences, IncUnited States$10.0025 g98%
TargetMol ChemicalsChina United States$40.002 g99.93%
TargetMol Chemicals EUAustria$56.001 g99.93%
MolnovaChina$74.00500 mg99%
MedChemExpress MCESweden$87.121 g99.94%
Labotest KGGermany$217.805000 mg90%
AngeneChina Hong Kong$4266.6730 mg98%
ChemDiv, Inc.United States$5480.0050 mg90%

Chemical Identity

CAS7365-45-9
PubChem CID23831
DTXSIDDTXSID5040382
FormulaC8H18N2O4S
Mol. Weight238.31 g/mol
SMILESC1CN(CCN1CCO)CCS(=O)(=O)O

Data Sources

DTXSID50403822026-04-06

https://doi.org/10.23645/epacomptox.5588566

Archive: data/sources/comptox/dsstox_identifiers.csv

238312026-04-06

https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/23831/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON

Archive: data/sources/pubchem_properties/23831.json

7365-45-92026-04-24

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr.csv

bulk match2026-04-07

https://open.fda.gov/data/ndc/

Archive: data/sources/fda/ndc/ndc.json