2,2',2''-Nitrilotrisacetonitrile

CAS 7327-60-8

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$281M

Top sourceChina 31%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292690 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Ion exchange agent in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS7327-60-8

PubChem CID81762

DTXSIDDTXSID3029285

FormulaC6H6N4

Mol. Weight134.14 g/mol

SMILESC(C#N)N(CC#N)CC#N

Data Sources

EPA CompTox (DSSTox) · DTXSID3029285Retrieved 2026-04-06
PubChem · compound 81762Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2,2',2''-Nitrilotrisacetonitrile (CAS 7327-60-8) https://chemicalindependence.com/chemical/7327-60-8/ EPA CompTox (DSSTox): DTXSID3029285. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3029285 PubChem: 81762. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/81762 EPA Chemical Data Reporting: 7327-60-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 7327-60-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292690 for CAS 7327-60-8. Reporting year: 2024. https://usatrade.census.gov/