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Estropipate

Drug ingredient

CAS 7280-37-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 7280-37-7
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
2 FDA-registered drug labelers
Productos Quimicos Naturales S.A. de C.V.
Sterling S.p.A.

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS7280-37-7
PubChem CID5284555
DTXSIDDTXSID3023005
FormulaC22H32N2O5S
Mol. Weight436.6 g/mol
SMILESCC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.C1CNCCN1

Data Sources

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Brief citations

Estropipate (CAS 7280-37-7) https://chemicalindependence.com/chemical/7280-37-7/ PubChem: 5284555. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5284555 FDA National Drug Code directory: CAS 7280-37-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 7280-37-7. Reporting year: 2024. https://usatrade.census.gov/