trypan blue

Drug ingredient

CAS 72-57-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$18M

Top sourceIndia 41%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 320414 · basket

These shares come from HS customs code 320414, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 41%IndiaMX 33%MexicoJP 8%JapanDE 6%GermanyTW 3%Taiwan

Malaysia
Italy
Canada
Czech Republic
Finland
Sweden
Australia
Brazil
Georgia
Switzerland

2 FDA-registered drug labelers

D.O.R.C. Dutch Ophthalmic Research Center (International) B.V.

Dutch Ophthalmic Research Center (International) B.V.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Visionblue
•Membraneblue

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1.86/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$185.80 / 100 g

PurityNot recorded

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$1.86	100 g	—

Chemical Identity

CAS72-57-1

PubChem CID6296

DTXSIDDTXSID4026268

FormulaC34H24N6Na4O14S4

Mol. Weight960.8 g/mol

SMILESCC1=C(C=CC(=C1)C2=CC(=C(C=C2)N=NC3=C(C4=C(C=C(C=C4C=C3S(=O)(=O)[O-])S(=O)(=O)[O-])N)O)C)N=NC5=C(C6=C(C=C(C=C6C=C5S(=O)(=O)[O-])S(=O)(=O)[O-])N)O.[Na+].[Na+].[Na+].[Na+]

Data Sources

PubChem · compound 6296Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

trypan blue (CAS 72-57-1) https://chemicalindependence.com/chemical/72-57-1/ PubChem: 6296. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6296 EPA TSCA Inventory: CAS 72-57-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 320414 for CAS 72-57-1. Reporting year: 2024. https://usatrade.census.gov/