doxycycline
Drug ingredientThis chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
Where It Comes From
41 FDA-registered drug labelers
A-S Medication Solutions
Advanced Rx Pharmacy of Tennessee, LLC
AiPing Pharmaceutical, Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Apotex Corp.
AvKARE
AvPAK
Bryant Ranch Prepack
Catalent Micron Technologies, Inc.
Catalent Pharma Solutions, LLC
Changzhou Pharmaceutical Factory
Chartwell Governmental & Specialty RX, LLC
Chartwell RX LLC
DIRECT RX
Dr.Reddys Laboratories Inc
Galderma Laboratories, L.P.
Golden State Medical Supply, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
HOVIONE FARMACIENCIA SA
Hovione PharmaScience Limited
Lannett Company, Inc.
Lupin Pharmaceuticals, Inc.
Macleods Pharmaceuticals Limited
Maithri Drugs Private Limited
Mayne Pharma Inc.
Nantong Chanyoo Pharmatech Co., Ltd
Northwind Health Company, LLC
NuCare Pharmaceuticals,Inc.
PD-Rx Pharmaceuticals, Inc.
Proficient Rx LP
Quality Care Products, LLC
REMEDYREPACK INC.
Solco Healthcare US,LLC
Strides Pharma Science Limited
Sun Pharmaceutical Industries Inc.
Yangzhou Liberty Pharmaceutical Co., Ltd.
Zoetis Inc.
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 3 drug and cosmetic product listings (FDA).
- •doxycycline
- •Doxycycline Monohydrate
- •Oracea
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
to be discontinued
Doxycycline Hyclate Tablet
06/13/2025to be discontinued
Doxycycline Hyclate Tablet
05/02/2025to be discontinued
Doxycycline Hyclate Tablet
01/12/2026Chemical Identity
CAS7164-70-7
PubChem CID54671203
DTXSIDDTXSID80992212
FormulaC22H24N2O8
Mol. Weight444.4 g/mol
SMILESCC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
Data Sources
546712032026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/doxycycline/cids/JSON
Archive: data/sources/pubchem_name/doxycycline.json
CAS 7164-70-72026-04-25
https://open.fda.gov/data/ndc/
Archive: data/sources/fda/ndc/ndc.json
CAS 7164-70-72026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json