2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole]

CAS 7128-64-5

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$6.4B

Top sourceSingapore 36%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499, 320420 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293499, 320420, which covers 590 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 6%India

Finland
Taiwan
Netherlands
Canada
Indonesia
Mexico
South Korea
Austria
Croatia
Sweden
Ukraine
Denmark
Israel
Czech Republic
New Zealand
Hong Kong
Kyrgyzstan
Australia
Portugal
South Africa
Poland
Slovenia
Brazil
Slovakia
Vietnam
Latvia
Malta
Hungary
Romania
Kenya
Belarus
Russia
Turkey
Armenia
Guatemala
Norway

EPA-registered importers (5)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Aalborz Chemical

Basf

Dow Chemical

Mayzo

Why It Matters

Sectors

ConstructionPlastics & RubberPaper & PrintingCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 3 functional roles.

•Antioxidant in Adhesive Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Brightener in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Brightener in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Monomers in Printing Ink ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.07/gAaron Chemicals LLC

CountryHong Kong

Pack$36.00 / 500 g

Purity98%

Vendors27 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

26 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.08	500 g	98%
A2B Chem LLC	United States	$0.09	1 kg	99%
AA BLOCKS	United States	$0.11	500 g	99%
Apollo Scientific US	United Kingdom	$0.12	500 g	99%
Chemscene	United States	$0.12	1 kg	—
BLD Pharmatech GmbH	Germany	$0.12	1 kg	98%
BLD Pharmatech Ltd.	China	$0.12	1 kg	98%
BLD Pharmatech Co., Limited	United States	$0.14	1 kg	98%
Ambeed, Inc.	United States	$0.14	1 kg	98%
Fluorochem EU	Germany	$0.17	100 g	97%
A2B Chem LLC (2 weeks)	United States	$0.20	500 g	—
AA BLOCKS (2 weeks)	United States	$0.22	500 g	—
Combi-Blocks, Inc.	United States	$0.25	1 kg	98%
AK Scientific Specialized	United States	$0.27	500 g	95%
AK Scientific, Inc.	United States	$0.36	500 g	98%
AstaTech (2 weeks)	United States	$1.17	100 g	95%
ALFA AESAR	Germany	$4.31	100 g	99%
Sigma-Aldrich (Rush Stock)	Germany	$17.71	5 g	99%
Sigma-Aldrich	Germany	$17.71	5 g	99%
Angene International Limited	United States	$52.20	5 g	99%
Labotest KG	Germany	$217.80	5000 mg	90%
ChemBridge Corporation	Kazakhstan	$1860.00	100 mg	90%
Vitas M Chemical Limited	Hong Kong	$4020.00	50 mg	90%
Princeton BioMolecular Research (SC)	United States	$4200.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS7128-64-5

PubChem CID292429

DTXSIDDTXSID1048205

FormulaC26H26N2O2S

Mol. Weight430.6 g/mol

SMILESCC(C)(C)C1=CC2=C(C=C1)OC(=N2)C3=CC=C(S3)C4=NC5=C(O4)C=CC(=C5)C(C)(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID1048205Retrieved 2026-04-06
PubChem · compound 292429Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole] (CAS 7128-64-5) https://chemicalindependence.com/chemical/7128-64-5/ EPA CompTox (DSSTox): DTXSID1048205. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1048205 PubChem: 292429. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/292429 EPA Chemical Data Reporting: 7128-64-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 7128-64-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293499,320420 for CAS 7128-64-5. Reporting year: 2024. https://usatrade.census.gov/