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Medroxyprogesterone acetate

Drug ingredient

CAS 71-58-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 71-58-9
US productionNot reported
Import value, 2024$76M
Top sourceSpain 35%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293723 · basket

These shares come from HS customs code 293723, which covers 29 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
ES 35%SpainNL 19%NetherlandsCN 18%ChinaIT 16%ItalyHU 4%Hungary
36 FDA-registered drug labelers
A-S Medication Solutions
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
Amphastar Nanjing Pharmaceuticals, Inc.
Amphastar Pharmaceuticals, Inc.
Bayer AG
Bryant Ranch Prepack
Coupler LLC
Curia Spain, S.A.U.
Eugia US LLC
Farmabios S.p.A.
Hikma Pharmaceuticals USA Inc.
Hubei Gedian Humanwell Pharmaceutical Co., Ltd.
LETCO MEDICAL, LLC
Mylan Institutional LLC
Mylan Pharmaceuticals Inc.
Northwind Health Company, LLC
NuCare Pharmaceuticals,Inc.
PD-Rx Pharmaceuticals, Inc.
Pfizer Ireland Pharmaceuticals Unlimited Company
Pharmacia & Upjohn Company LLC
Pharmacia and Upjohn Company LLC
PharmPak, Inc.
Prasco Laboratories
Preferred Pharmaceuticals Inc.
Proficient Rx LP
REMEDYREPACK INC.
Sicor de Mexico S.A. de C.V
Sotera Health LLC
STERLING SPA
Sun Pharmaceutical Industries, Inc.
Teva Pharmaceuticals USA, Inc.
Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.
Xiromed LLC
Zhejiang Xianju Pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Medroxyprogesterone Acetate
  • •Medroxyprogesterone Acetate Injectable Suspension
  • •Depo-Provera
  • •Provera
  • •Depo-SubQ Provera
  • •Prempro
  • •Medroxyprogesterone
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS71-58-9
PubChem CID6279
DTXSIDDTXSID0025527
FormulaC24H34O4
Mol. Weight386.5 g/mol
SMILESCC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C

Data Sources

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Brief citations

Medroxyprogesterone acetate (CAS 71-58-9) https://chemicalindependence.com/chemical/71-58-9/ PubChem: 6279. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6279 EPA TSCA Inventory: CAS 71-58-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293723 for CAS 71-58-9. Reporting year: 2024. https://usatrade.census.gov/