Benzene
Drug ingredientCAS 71-43-2
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$1.5B
Top sourceSouth Korea 49%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 290220 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
KR 49%South KoreaNL 10%NetherlandsCA 10%CanadaSA 7%Saudi ArabiaJP 6%Japan
- Israel
- Germany
- China
- Poland
EPA-registered manufacturers (39)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Cenovus Energy · CA Canada
Indorama Netherlands Bv · NL Netherlands
Ineos · GB United Kingdom
Pdvsa Petroleos S A · VE Venezuela
Show all 39
Shell Plc · GB United Kingdom
Shin-Etsu Chemical · JP Japan
Totalenergies Se · FR France
Advansix
Basf
Chalmette Refining
Chevron
Chevron Phiillips Chemical
Chevron Phillips Chemical
Deer Park Refining
Delek Us Holdings
Dow Chemical
Dupont Specialty Products Usa
Dynachem
ExxonMobil
Gulf Coast Growth Ventures
Indorama Ventures Oxides
Ineos Us Petrochem
Lima Refining
Lone Star Specialty Products
Lyondell Chemical
Marathon Petroleum
Nippon Chemical Texas
Pbf Holding
Pdv Holding
Phillips 66
Richard-Allan Scientific
Shell Chemical Appalachia
Shell Petroleum
Shintech Louisiana
The Goodyear Tire & Rubber
Totalenergies Holdings Usa
Trafigura Trading
Wrb Refining
Domestic parents -- activity not disclosed (14)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
BP
Deltech Monomers Bidco Holdings
Eastman Chemical
Huntsman
Koch Industries
Show all 14
Lanxess
Marubeni America
Motiva Enterprises
Repsol Energy North America
Rio Energy International
Samsung C&T America
Sumitomo Corporation Of Americas
Tartan Oil
Valero Energy
EPA-registered importers (20)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Brenntag · DE Germany
Canada Imperial Oil · CA Canada
Shell Plc · GB United Kingdom
Total Se · FR France
Brenntag Global Marketing
Show all 20
Covestro
Eneos Americas
George E. Warren
Gunvor Usa
Icc Industries
Ies Downstream
Ineos Styrolution America
Mie
Mitsubishi Corporation (Americas)
Par Pacific Holdings
Peerless Oil & Chemicals
Suno
Total Holdings Usa
Tricon International
World Fuel Services
11 FDA-registered drug labelers
Apex Energetics Inc.
BioActive Nutritional
BioActive Nutritional, Inc.
Boiron
Deseret Biologicals, Inc.
Energetix Corporation
Energique, Inc.
Nucleic Products, LLC
Nutritional Specialties, Inc.
Professional Complementary Health Formulas
Vitality Works, Inc.
Why It Matters
Sectors
HealthEnergyElectronicsConstructionMetals & MiningPlastics & RubberConsumer ProductsCore Chemicals
Downstream Uses
Appears in 20 drug and cosmetic product listings (FDA).
- •Industriox
- •Household Detox
- •Petrochemical Detox
- •Industriox 6011
- •Perfumox 6028
- •Pneumotox
- •Household Antigens
- •Epl-Cell Repair
Show all 20
- •Enviroclenz
- •Benzinum
- •Enviro Detox 6009
- •Toxagent Detox 6035
- •Isopathic Phenolic Rings
- •N02 Petrochem
- •Pollutox
- •Hypothaltem
- •Solvent/Small Ring Combination 9317
- •Tobaccotox
- •Envirotox
- •L-Trans
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 16 sectors as 15 functional roles.
- •Fuel agents in Petroleum Refineries (100%)Processing as a reactant
- •Solvent in Petrochemical Manufacturing (100%)Processing as a reactant
- •Intermediate in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel in Petroleum Refineries (70%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Plastics Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solvent in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
- •Intermediate in Cyclic Crude and Intermediate ManufacturingProcessing as a reactant
- •Intermediate in Rubber Product ManufacturingProcessing as a reactant
- •Intermediate in Plastics Product ManufacturingProcessing as a reactant
- •Plasticizer in Petroleum Refineries (100%)Processing—repackaging
- •Fuel agents in Petrochemical ManufacturingProcessing as a reactant
- •Binder in Wood Product Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Organic Chemical Manufacturing (87%)Processing as a reactant
- •Intermediate in Wholesale and Retail Trade (13%)Processing—repackaging
- •Intermediate in Petroleum Refineries (30%)Processing as a reactant
- •Fuel in Wholesale and Retail Trade (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Oil and Gas Drilling, Extraction, and Support activities (100%)Use—non-incorporative activities
- •Intermediate in Plastics Material and Resin Manufacturing (32%)Processing as a reactant
- •Heat transferring agent in Petrochemical Manufacturing (1%)Processing as a reactant
- •Flame retardant in Petrochemical Manufacturing (2%)Processing as a reactant
- •Plasticizer in Petrochemical Manufacturing (3%)Processing as a reactant
- •Surfactant (surface active agent) in Petrochemical Manufacturing (8%)Processing as a reactant
- •pH regulating agent in All Other Chemical Product and Preparation Manufacturing (100%)Use—non-incorporative activities
- •Fuel in All other Petroleum and Coal Products Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel in Petrochemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Other (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Plasticizer in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Adhesion/cohesion promoter in Adhesive ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Fuel agents in Wholesale and Retail Trade (20%)Processing—repackaging
- •Intermediate in Computer and Electronic Product Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in All Other Basic Organic Chemical Manufacturing (95%)Processing as a reactant
- •Laboratory chemicals in Other (20%)Processing—repackaging
- •Processing aids, specific to petroleum production in Petroleum RefineriesProcessing as a reactant
Chemical Identity
CAS71-43-2
PubChem CID241
DTXSIDDTXSID3039242
FormulaC6H6
Mol. Weight78.11 g/mol
SMILESC1=CC=CC=C1
Data Sources
- EPA CompTox (DSSTox) · DTXSID3039242Retrieved 2026-04-06
- PubChem · compound 241Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Benzene (CAS 71-43-2) https://chemicalindependence.com/chemical/71-43-2/ EPA CompTox (DSSTox): DTXSID3039242. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3039242 PubChem: 241. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/241 EPA Chemical Data Reporting: 71-43-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 71-43-2. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 290220 for CAS 71-43-2. Reporting year: 2024. https://usatrade.census.gov/