Doxofylline

Drug ingredient

CAS 69975-86-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$6M

Top sourceChina 50%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293959 · basket

These shares come from HS customs code 293959, which covers 9 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 50%ChinaIN 39%IndiaPL 6%PolandIT 4%ItalyDE 1%Germany

United Kingdom

1 FDA-registered drug labeler

Cohance Lifesciences Limited

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.55/gAaron Chemicals LLC

CountryHong Kong

Pack$275.00 / 500 g

Purity99%

Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.59	500 g	98%
A2B Chem LLC	United States	$1.03	500 g	98%
AA BLOCKS	United States	$1.35	500 g	98%
AK Scientific, Inc.	United States	$13.60	5 g	98%
AstaTech (2 weeks)	United States	$19.96	25 g	95%
Cayman Europe	Estonia	$24.04	25 g	98%
Angene International Limited	United States	$28.00	5 g	98%
Interbioscreen	Hong Kong	$34.00	10 g	95%
MedKoo Biosciences, Inc	United States	$95.00	10 g	98%
Molnova	China	$430.00	100 mg	99%
TargetMol Chemicals	China → United States	$480.00	100 mg	99.99%
MedChemExpress MCE	Sweden	$750.20	100 mg	99.97%
Apexbio Technology LLC	United States	$1000.00	50 mg	99.99%
Axon Medchem	Netherlands	$1200.00	50 mg	99%
Sigma-Aldrich (Rush Stock)	Germany	$3716.00	50 mg	98%
Sigma-Aldrich	Germany	$3716.00	50 mg	98%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Vitas M Chemical Limited	Hong Kong	$6250.00	20 mg	90%
Princeton BioMolecular Research (SC)	United States	$6500.00	20 mg	90%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS69975-86-6

PubChem CID50942

DTXSIDDTXSID7022968

FormulaC11H14N4O4

Mol. Weight266.25 g/mol

SMILESCN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3

Data Sources

PubChem · compound 50942Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Doxofylline (CAS 69975-86-6) https://chemicalindependence.com/chemical/69975-86-6/ PubChem: 50942. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/50942 FDA National Drug Code directory: CAS 69975-86-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293959 for CAS 69975-86-6. Reporting year: 2024. https://usatrade.census.gov/