Cyclomethicone

Drug ingredient

CAS 69430-24-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$697M

Top sourceGermany 27%

EPA lists this chemical for 2019 but publishes zero or no volume for both production and imports.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 391000 · basket

EPA reports by year

2019: US production Not published · Imports Not published

These shares come from HS customs code 391000, which covers 22 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 27%GermanyJP 22%JapanCA 12%CanadaCN 11%ChinaIT 9%Italy

Netherlands
Taiwan
Indonesia
Ireland
Mexico
New Zealand
Hungary
Sweden
Turkey
Norway
Colombia
Switzerland
Austria
Trinidad and Tobago
Australia
Hong Kong
Denmark
Finland
United Arab Emirates
Poland
Portugal
Israel
Singapore
Argentina
Slovenia
Costa Rica
Russia
Dominican Republic
Luxembourg
Romania
Peru
South Africa
Lithuania
Serbia
Liechtenstein
Philippines
Monaco
Latvia
Cambodia
Saudi Arabia

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Brenntag

1 FDA-registered drug labeler

Jiangxi Yudexi Pharmaceutical Co., LTD

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Dermfree SCAR Sheets

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS69430-24-6

PubChem CIDNot recorded

DTXSIDDTXSID8041820

FormulaNot recorded

Mol. WeightNot recorded

SMILESNot recorded

Data Sources

EPA CompTox (DSSTox) · DTXSID8041820Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Cyclomethicone (CAS 69430-24-6) https://chemicalindependence.com/chemical/69430-24-6/ EPA CompTox (DSSTox): DTXSID8041820. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8041820 EPA Chemical Data Reporting: 69430-24-6. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 69430-24-6. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 391000 for CAS 69430-24-6. Reporting year: 2024. https://usatrade.census.gov/