D-Mannitol

Drug ingredient

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 69-65-8
US ProductionCBI
Import Value$46M
Top SourceItaly 78%

The EPA did not publish how much of this chemical companies made or imported, or marked that amount confidential. Without that volume, ACID cannot calculate import dependency.

Where It Comes From

Customs basis: HS 290543 · exact

Source Countries
IT 78%ItalyCN 18%ChinaDE 2%GermanyIN 2%India
EPA-registered manufacturers (1)
Roquette America
EPA-registered importers (2)
Avantor
Emd Holding

Why It Matters

Sectors
Core ChemicalsHealth
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Mannitol
  • •Osmitrol
  • •QR PAIN
  • •Sorbitol-Mannitol
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 1 sector as 1 functional role.

  • •Laboratory chemicals in All Other Chemical Product and Preparation ManufacturingProcessing—repackaging

Vendor Pricing

$0.50/gA2B Chem LLC
CountryUnited States
Pack$50.00 / 100 g
Purity95%
Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors
VendorCountry$/gPackPurity
Combi-Blocks, Inc.United States$0.50100 g95%
AA BLOCKSUnited States$0.63100 g95%
Aaron Chemicals LLCHong Kong$70.6425 g50%
Angene ChemicalChina → Hong Kong$71.0025 g50%
Angene International LimitedUnited States$96.805 g98%
Chengdu Biopurify Phytochemicals Ltd.China$142.001 g98%
Labotest KGGermany$217.805000 mg90%
ChemFacesChina$1500.0020 mg98%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
TimTec, LLC (back-ordered)United States$32000.0015 mg94%

Chemical Identity

CAS69-65-8
PubChem CID6251
DTXSIDDTXSID1023235
FormulaC6H14O6
Mol. Weight182.17 g/mol
SMILESC(C(C(C(C(CO)O)O)O)O)O

Data Sources

DTXSID10232352026-04-06

https://doi.org/10.23645/epacomptox.5588566

Archive: data/sources/comptox/dsstox_identifiers.csv

62512026-04-06

https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/6251/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON

Archive: data/sources/pubchem_properties/6251.json

69-65-82026-04-24

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr.csv

CAS 69-65-82026-04-25

https://www.epa.gov/chemical-data-reporting

Archive: data/sources/epa_cdr/2020_cdr_industrial.csv

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