Hexafluoroacetone

CAS 684-16-2

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$175M

Top sourceIndia 48%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291479 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291479, which covers 95 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 48%IndiaCN 20%ChinaMX 19%MexicoDE 10%GermanyFI 2%Finland

Ukraine
Japan
Australia
Netherlands
South Korea
Canada
Switzerland
Russia
Poland
Italy
United Kingdom
Spain
Taiwan
Grenada

Why It Matters

Sectors

Metals & Mining

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Miscellaneous ManufacturingProcessing as a reactant

Vendor Pricing

$5.85/gA2B Chem LLC (1 week)

CountryUnited States

Pack$585.00 / 100 g

Purity97%

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
AA BLOCKS (1 week)	United States	$6.18	100 g	—

Chemical Identity

CAS684-16-2

PubChem CID12695

DTXSIDDTXSID9043778

FormulaC3F6O

Mol. Weight166.02 g/mol

SMILESC(=O)(C(F)(F)F)C(F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID9043778Retrieved 2026-04-06
PubChem · compound 12695Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Hexafluoroacetone (CAS 684-16-2) https://chemicalindependence.com/chemical/684-16-2/ EPA CompTox (DSSTox): DTXSID9043778. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9043778 PubChem: 12695. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12695 EPA Chemical Data Reporting: 684-16-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 684-16-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291479 for CAS 684-16-2. Reporting year: 2024. https://usatrade.census.gov/