2-Ethylhexyl ((3-((2-(dimethylamino)ethoxy)carbonyl)amino)-4-methylphenyl)carbamate, 2-hydroxy-propanoic acid salt

CAS 68227-46-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$872M

Import volumeZero

Top sourceSwitzerland 44%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292429 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292429, which covers 203 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 44%SwitzerlandCN 19%ChinaIN 12%IndiaJP 9%JapanIE 6%Ireland

Taiwan
United Kingdom
El Salvador
Colombia
Ukraine
Brazil
Guatemala
Belgium
Netherlands
Turkey
Sweden
Greece
Canada
Israel
New Zealand
Latvia
Lithuania
Finland
Slovakia
Australia
Hong Kong
Czech Republic
Armenia
Poland

Why It Matters

Sectors

Plastics & RubberPaints & Coatings

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 1 functional role.

•Intermediate in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
•Intermediate in Paint and Coating Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS68227-46-3

PubChem CID6437503

DTXSIDDTXSID3028421

FormulaC24H41N3O7

Mol. Weight483.6 g/mol

SMILESCCCCC(CC)COC(=O)NC1=CC(=C(C=C1)C)NC(=O)OCCN(C)C.CC(C(=O)O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID3028421Retrieved 2026-04-06
PubChem · compound 6437503Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Ethylhexyl ((3-((2-(dimethylamino)ethoxy)carbonyl)amino)-4-methylphenyl)carbamate, 2-hydroxy-propanoic acid salt (CAS 68227-46-3) https://chemicalindependence.com/chemical/68227-46-3/ EPA CompTox (DSSTox): DTXSID3028421. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3028421 PubChem: 6437503. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6437503 EPA Chemical Data Reporting: 68227-46-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 68227-46-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292429 for CAS 68227-46-3. Reporting year: 2024. https://usatrade.census.gov/