Tetramethyl orthosilicate

CAS 681-84-5

Silicic acid (H4SiO4), tetramethyl ester

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$208M

Top sourceChina 28%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292090 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential

These shares come from HS customs code 292090, which covers 98 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 28%ChinaKR 17%South KoreaIT 13%ItalyIN 10%IndiaDE 9%Germany

Poland
Switzerland
Ireland
Canada
Lithuania
Netherlands
Brazil
Malaysia
Hungary
Czech Republic
Saudi Arabia
Slovakia
Ukraine
Turkey

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Kcc · KR South Korea

Mom Holding

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Inorganic Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.47/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$233.26 / 500 g

Purity98%

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.47	500 g	98%

Chemical Identity

CAS681-84-5

PubChem CIDNot recorded

DTXSIDDTXSID3027291

FormulaC4H12O4Si

Mol. Weight152.221 g/mol

SMILESCO[Si](OC)(OC)OC

Data Sources

EPA TSCA InventoryRetrieved 2026-04-29
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Tetramethyl orthosilicate (CAS 681-84-5) https://chemicalindependence.com/chemical/681-84-5/ EPA TSCA Inventory: CAS 681-84-5. Retrieved 2026-04-29. https://www.epa.gov/tsca-inventory EPA Chemical Data Reporting: 681-84-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 681-84-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292090 for CAS 681-84-5. Reporting year: 2024. https://usatrade.census.gov/