Hydroxyzine

Drug ingredient

CAS 68-88-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

2 FDA-registered drug labelers

Emcure Pharmaceuticals Limited

Srikem Laboratories Pvt. Ltd.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1.90/gMedKoo Biosciences, Inc

CountryUnited States

Pack$950.00 / 500 g

Purity98%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
ACINTS	United Kingdom	$193.44	5 g	95%
Aaron Chemicals LLC	Hong Kong	$331.00	1 g	—
A2B Chem LLC	United States	$560.00	50 mg	99.54%
AA BLOCKS	United States	$642.00	500 mg	99.54%
TargetMol Chemicals	China → United States	$720.00	50 mg	99.54%
MedChemExpress MCE	Sweden	$810.70	100 mg	99.72%
Angene International Limited	United States	$2780.00	100 mg	95%
Molnova	China	$12780.00	100 mg	99%

Chemical Identity

CAS68-88-2

PubChem CID3658

DTXSIDDTXSID8023137

FormulaC21H27ClN2O2

Mol. Weight374.9 g/mol

SMILESC1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Data Sources

PubChem · compound 3658Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Hydroxyzine (CAS 68-88-2) https://chemicalindependence.com/chemical/68-88-2/ PubChem: 3658. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3658 FDA National Drug Code directory: CAS 68-88-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 68-88-2. Reporting year: 2024. https://usatrade.census.gov/