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Norethindrone

Drug ingredient

CAS 68-22-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 68-22-4
US productionNot reported
Import value, 2024$76M
Top sourceSpain 35%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293723 · basket

These shares come from HS customs code 293723, which covers 29 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
ES 35%SpainNL 19%NetherlandsCN 18%ChinaIT 16%ItalyHU 4%Hungary
21 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Afaxys Pharma, LLC
Apotex Corp.
Aspen Oss B.V.
Aurobindo Pharma Limited
Bayer AG
Brichem Sciences Private Limited
Dr. Reddy's Labratories Inc.
Glenmark Pharmaceuticals Inc., USA
Lupin Pharmaceuticals, Inc.
Mayne Pharma Inc.
Mylan Pharmaceuticals Inc.
Naari Pte. Limited
PD-Rx Pharmaceuticals, Inc.
Proficient Rx LP
SCH Global Services Private Limited
Teva Pharmaceuticals USA, Inc.
Teva Pharmaceuticals, Inc.
Valdepharm
Xiromed LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 13 drug and cosmetic product listings (FDA).

  • •Norethindrone
  • •Jencycla
  • •Nora BE
  • •Heather
  • •Errin
  • •Camila
  • •Incassia
  • •Nortrel 21 Day
Show all 13
  • •Affodel
  • •Orquidea
  • •Meleya
  • •Lyleq
  • •Emzahh
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS68-22-4
PubChem CID6230
DTXSIDDTXSID9023380
FormulaC20H26O2
Mol. Weight298.4 g/mol
SMILESCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34

Data Sources

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Brief citations

Norethindrone (CAS 68-22-4) https://chemicalindependence.com/chemical/68-22-4/ PubChem: 6230. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6230 FDA National Drug Code directory: CAS 68-22-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293723 for CAS 68-22-4. Reporting year: 2024. https://usatrade.census.gov/