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cyanocobalamin

Drug ingredient

CAS 68-19-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 68-19-9
1 Co²⁺
US productionNot reported
Import value, 2024$70M
Top sourceChina 85%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293626 · narrow

These shares come from HS customs code 293626, which covers 4 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 85%ChinaES 9%SpainIN 3%IndiaIT 2%ItalyPT 1%Portugal
62 FDA-registered drug labelers
A-S Medication Solutions
Acella Pharmaceuticals, LLC
American Regent, Inc.
Asclemed USA, Inc.
AuroMedics Pharma LLC
Avion Pharmaceuticals, LLC
AX Pharmaceutical Corp
BioActive Nutritional, Inc.
Blue Heron Pharmaceuticals, LLC
BluePoint Laboratories
BonGeo Pharmaceuticals, Inc.
Bryant Ranch Prepack
CarWin Pharmaceutical Associates, LLC
DNA Labs, Inc.
DSM Nutritional Products, LLC
Elanco US Inc.
ENDO USA, Inc.
EUROAPI FRANCE
Exeltis USA, Inc.
Florrax Pharmaceutical
Fresenius Kabi USA, LLC
Gland Pharma Limited
Hebei Huarong Pharmaceutical Co., Ltd.
Henry Schein, Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
Interquim, S.A. de C.V.
LETCO MEDICAL, LLC
Lifestar Pharma LLC
Lupin Pharmaceuticals,Inc.
Medilane Healthcare Pvt Ltd
Medisca Inc.
Meitheal Pharmaceuticals Inc.
METHOD PHARMACEUTICALS, LLC
Mission Pharmacal Company
Nnodum Pharmaceuticals
NorthStar RxLLC
Oncora Pharma, LLC
Padagis Israel Pharmaceuticals Ltd
Patrin Pharma, Inc.
Plano Pharmaceuticals Inc.
ProBLEN
Professional Complementary Health Formulas
Professional Compounding Centers of America
PureTek Corporation
REMEDYREPACK INC.
Sagent Pharmaceuticals
Sandoz Inc
Sanofi chimie
SCH Global Services Private Limited
Seton Pharmaceuticals
SOLA Pharmaceuticals
Somerset Therapeutics, LLC
Sportpharm LLC
U.S. Pharmaceutical Corporation
Vitruvias Therapeutics
Willow Birch Pharma, Inc.
Willow Birch Pharma, LLC
WINDER LABORATORIES, LLC
WOMENS CHOICE PHARMACEUTICALS LLC
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 74 drug and cosmetic product listings (FDA).

  • •Cyanocobalamin
  • •Quflora Pediatric
  • •Telomere - DNA
  • •Nascobal
  • •Nestabs Prenatal Multi-vitamin/Mineral Supplement
  • •Floriva
  • •Multivitamin with Fluoride
  • •Flotrex
Show all 74
  • •Prenatryl
  • •Ventrixyl Fe
  • •B-Balance Liquescence 3003
  • •Vitafol One
  • •Vitafol Fe Plus
  • •Aflora
  • •Concept OB
  • •D-138
  • •M-Natal Plus
  • •Vitrexate
  • •Venexa
  • •Prenate Restore
  • •Prenate Pixie
  • •Floravita Mini
  • •Folartex
  • •Folixia
  • •Nutralyn
  • •Se-Tan PLUS
  • •PNV-Omega
  • •PureVit DualFe Plus
  • •Vitranol Fe
  • •Pretrate
  • •Folitin-Z
  • •Multi-Vit-Flor
  • •Prenate Enhance
  • •Prenatal Vitamins Plus Low Iron
  • •Prenatrix
  • •Multitam
  • •Prenate Elite
  • •Prenate Mini
  • •TriStart DHA
  • •Vitrexyl plus Iron
  • •Ribotin-E
  • •Prenate Essential
  • •Folaten
  • •PNV-Select
  • •Occuloplex I
  • •Vitrexate FE
  • •Ventrixyl
  • •Vitramyn
  • •Davimet
  • •Tricon
  • •Vitafol Ultra
  • •BP Vit 3
  • •Nestabs ONE
  • •Foliflex
  • •Prenatal Plus Vitamins
  • •Prenate DHA
  • •Niferex
  • •Strovite One Caplets
  • •Matronex
  • •Se-Natal 19 Chewable
  • •Pediatric Infuvite Multiple Vitamins
  • •Vitrexyl
  • •Vitranol
  • •Zintrexyl-C
  • •Dexatran
  • •Se-Natal 19
  • •Concept DHA
  • •SAMe Liquescence 3036
  • •PNV-DHA
  • •Ferralet 90
  • •Prometa
  • •Venexa FE
  • •Prenate Chewable
  • •Chromagen
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS68-19-9
PubChem CID166596686
DTXSIDDTXSID7044346
FormulaC63H88CoN14O14P
Mol. Weight1355.4 g/mol
SMILESCC1=CC2=C(C=C1C)[N+](=CN2)C3C(C(C(O3)CO)OP(=O)(O)OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=N)[O-])N7)CCC(=N)[O-])(C)CC(=O)N)C)CCC(=N)[O-])(C)CC(=O)N)C)CC(=O)N)C)O.[C]#N.[Co+2]

Data Sources

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Brief citations

cyanocobalamin (CAS 68-19-9) https://chemicalindependence.com/chemical/68-19-9/ PubChem: 166596686. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/166596686 EPA TSCA Inventory: CAS 68-19-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293626 for CAS 68-19-9. Reporting year: 2024. https://usatrade.census.gov/