3,3,3-Trifluoro-1-propene

CAS 677-21-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$48M

Top sourceChina 36%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290359 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290359, which covers 16 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 36%ChinaDE 35%GermanyJP 21%JapanKR 5%South KoreaIN 1%India

Italy
Spain
Malaysia
Ukraine

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Chemours

Why It Matters

Sectors

EnergyCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 1 functional role.

•Intermediate in Cyclic Crude and Intermediate Manufacturing (10%)Processing as a reactant
•Intermediate in All Other Basic Organic Chemical Manufacturing (90%)Processing as a reactant
•Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS677-21-4

PubChem CID12672

DTXSIDDTXSID9041287

FormulaC3H3F3

Mol. Weight96.05 g/mol

SMILESC=CC(F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID9041287Retrieved 2026-04-06
PubChem · compound 12672Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

3,3,3-Trifluoro-1-propene (CAS 677-21-4) https://chemicalindependence.com/chemical/677-21-4/ EPA CompTox (DSSTox): DTXSID9041287. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9041287 PubChem: 12672. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12672 EPA Chemical Data Reporting: 677-21-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 677-21-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290359 for CAS 677-21-4. Reporting year: 2024. https://usatrade.census.gov/