cholecalciferol

Drug ingredient

CAS 67-97-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 67-97-0
US productionNot reported
Import value, 2024$6.8B
Top sourceSingapore 40%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 210690 · narrow

These shares come from HS customs code 210690, which covers 2 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 40%SingaporeCA 16%CanadaCN 8%ChinaMX 4%MexicoDE 3%Germany
35 FDA-registered drug labelers
A-S Medication Solutions
Acella Pharmaceuticals, LLC
Avion Pharmaceuticals, LLC
AX Pharmaceutical Corp
Blue Heron Pharmaceuticals, LLC
BonGeo Pharmaceuticals, Inc.
Bryant Ranch Prepack
CarWin Pharmaceutical Associates, LLC
CUSTICS
DARMERICA, LLC
Deseret Biologicals, Inc.
DSM Nutritional Products LLC
Exeltis USA, Inc.
Florrax Pharmaceutical
Guna spa
Hillestad Pharmaceuticals USA
InLight Creation, LLC.
Method Pharmaceuticals, LLC
Nutritional Specialties, Inc.
Oncora Pharma LLC
Organon LLC
Patrin Pharma, Inc.
ProBLEN
Pure Source, LLC
PureTek Corporation
QINGDAO TIDA BIOTEK CO.,LTD
REMEDYREPACK INC.
ROVI Pharma Industrial Services SA
Sandoz Inc
Seton Pharmaceuticals
V2 Pharma LLC
WINDER LABORATORIES, LLC
WOMENS CHOICE PHARMACEUTICALS LLC
Zhejiang Nhu Co. Ltd.
ZUVCHEM

Why It Matters

Sectors
Health
Downstream Uses

Appears in 87 drug and cosmetic product listings (FDA).

  • •Folvitra
  • •Quflora Pediatric
  • •PNV-DHA
  • •Energy Catalyst
  • •Telomere - DNA
  • •Nestabs Prenatal Multi-vitamin/Mineral Supplement
  • •Floriva
  • •Flotrex
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS67-97-0
PubChem CID5280795
DTXSIDDTXSID6026294
FormulaC27H44O
Mol. Weight384.6 g/mol
SMILESCC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C

Data Sources

Brief citations

cholecalciferol (CAS 67-97-0) https://chemicalindependence.com/chemical/67-97-0/ PubChem: 5280795. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5280795 EPA TSCA Inventory: CAS 67-97-0. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 210690 for CAS 67-97-0. Reporting year: 2024. https://usatrade.census.gov/