Nitrofurantoin

Drug ingredient

CAS 67-20-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$6.4B

Top sourceSingapore 36%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India

Finland
Netherlands
Canada
Indonesia
Mexico
Taiwan
South Korea
Austria
Croatia
Sweden
Ukraine
Denmark
Israel
Czech Republic
New Zealand
Hong Kong
Kyrgyzstan
Australia
Portugal
South Africa
Poland
Slovenia
Brazil
Slovakia
Vietnam
Latvia
Malta
Hungary
Romania
Kenya
Belarus
Russia
Turkey
Norway

56 FDA-registered drug labelers

A-S Medication Solutions

Alembic Pharmaceuticals Inc.

Alembic Pharmaceuticals Limited

Almatica Pharma LLC

Alvogen Inc.

American Health Packaging

Amneal Pharmaceuticals LLC

Amneal Pharmaceuticals NY LLC

Amneal Pharmaceuticals of New York LLC

ANI Pharmaceuticals, Inc.

Arch Pharmalabs Limited

Asclemed USA, Inc.

ASolution Pharmaceutical Private Limited

Aurobindo Pharma Limited

AvPAK

Biocon Pharma Inc

BluePoint Laboratories

BluePoint Labortories

Bryant Ranch Prepack

Camber Pharmaceuticals, Inc.

DARMERICA, LLC

Derivados Quimicos

Direct_Rx

F.I.S. FABBRICA ITALIANA SINTETICI S.P.A.

Jubilant Cadista Pharmaceuticals Inc.

Lifestar Pharma LLC

Lupin Pharmaceuticals,Inc.

Maithri Drugs Private Limited

Major Pharmaceuticals

Micro Labs Limited

NCS HealthCare of KY, LLC dba Vangard Labs

NorthStar Rx LLC

Northwind Health Company, LLC

Novel Laboratories, Inc.

NuCare Pharmaceuticals,Inc.

Nuray Chemicals Private Limited

PAI Holdings, LLC dba PAI Pharma

PD-Rx Pharmaceuticals, Inc.

PharmPak, Inc.

Preferred Pharmaceuticals Inc.

Proficient Rx LP

Qingdao Biopeptek Co., Ltd.

QPharma, Inc.

Redpharm Drug

Redpharm Drug, Inc.

REMEDYREPACK INC.

Rising Pharma Holdings, Inc.

Sandoz Inc

Somerset Therapeutics, LLC

ST. MARY'S MEDICAL PARK PHARMACY

Sun Pharmaceutical Industries, Inc.

Trigen Laboratories, LLC

TYCHE INDUSTRIES LIMITED

VERITYRX, LLC

Zydus Lifesciences Limited

Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 11 drug and cosmetic product listings (FDA).

•Nitrofurantoin
•Nitrofurantion
•Nitrofurantoin (monohydrate/macrocrystals)
•Nitrofurantoin Monohydrate/Macrocrystal
•nitrofurantoin macrocrystals
•Nitrofurantion Macrocrystals
•Nitrofurantoin Mono
•Nitrofurantoin Monohydrate/ Macrocrystalline

Show all 11

•Macrodantin
•Macrobid
•Nitrofurantoin Oral Suspension

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Nitrofurantoin Oral Suspension
Shortage listed since April 10, 2026

See all current drug shortages

Vendor Pricing

$0.33/gAaron Chemicals LLC

CountryHong Kong

Pack$167.00 / 500 g

Purity98%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.37	500 g	98%
Fulfilled by Molport	Latvia	$5.00	1 g	98%
TargetMol Chemicals	China → United States	$53.00	1 g	99.99%

Chemical Identity

CAS67-20-9

PubChem CID6604200

DTXSIDDTXSID7020972

FormulaC8H6N4O5

Mol. Weight238.16 g/mol

SMILESC1C(=O)NC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]

Data Sources

PubChem · compound 6604200Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Nitrofurantoin (CAS 67-20-9) https://chemicalindependence.com/chemical/67-20-9/ PubChem: 6604200. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6604200 EPA TSCA Inventory: CAS 67-20-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 67-20-9. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293499 for CAS 67-20-9. Reporting year: 2024. https://usatrade.census.gov/