Flag of the United StatesAmerican Chemical Independence

Thiamine hydrochloride

Drug ingredient

CAS 67-03-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 67-03-8
1 Cl⁻ · 1 HCl
US productionNot reported
Import value, 2024$49M
Top sourceChina 88%

EPA lists this chemical for 2019 but publishes zero or no volume for both production and imports.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293622 · basket

EPA reports by year
2019
US production Not published · Imports Not published

These shares come from HS customs code 293622, which covers 5 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 88%ChinaDE 10%GermanyJP 2%JapanIN 1%India
Domestic parents -- activity not disclosed (1)
Brenntag
43 FDA-registered drug labelers
Apotheca Company
Armas Pharmaceuticals Inc.
BioActive Nutritional, Inc.
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Caplin Steriles Limited
CarWin Pharmaceutical Associates, LLC
Cohance Lifesciences Limited
Deseret Biologicals, Inc.
DNA Labs, Inc.
Dr. Donna Restivo DC
Dr. Reddy's Laboratories Inc.
DSM Nutritional Products LLC
Eight and Company L.L.C
Energetix Corporation
Energique, Inc.
Eugia US LLC
Fosun Pharma USA Inc.
Fresenius Kabi USA, LLC
Gland Pharma Limited
Guna spa
Henry Schein, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
InLight Creation, LLC.
Integrative Health Alliance
Jiangxi Tianxin Pharmaceutical Co., Ltd.
Medisca Inc.
Method Pharmaceuticals, LLC
Mylan Institutional LLC
Natural Creations, Inc
NorthStar Rx LLC
Nutritional Specialties, Inc.
Oncora Pharma, LLC
ONESOURCE SPECIALTY PHARMA LIMITED
Professional Compounding Centers of America dba PCCA
REMEDYREPACK INC.
Sagent Pharmaceuticals
Sandoz Inc
Sionc Pharmaceutical Private Limited
STHREE CHEMICALS PRIVATE LIMITED
Topchem Pharmaceuticals Ltd

Why It Matters

Sectors
Health
Downstream Uses

Appears in 41 drug and cosmetic product listings (FDA).

  • •Thiamine Hydrochloride
  • •Quflora Pediatric
  • •FCS CP
  • •Spinalmax
  • •Dynamic Brain
  • •Glucoreg
  • •Thiamine HCl
  • •Thiamine Hydrochloride injection, solution
Show all 41
  • •Thiamine
  • •GUNA-Liver
  • •FCS HP
  • •Bio Cytotox Phase
  • •Bio Co-Enzyme Phase
  • •Mitochondria PRO
  • •D-76
  • •Neuro-Chord
  • •Multi-Vit-Flor
  • •GUNA-Digest
  • •TriStart DHA
  • •Adaptagen
  • •Mast Cell Pro
  • •Lunavira
  • •GUNA-Dizzy
  • •GUNA-CELL
  • •Viru-Chord
  • •B Complex Liquescence
  • •Omeosport
  • •Sinus Tonic
  • •Hair and Nail Tonic
  • •Vitamin B Complex
  • •Cellular Oxygenator
  • •Lumavex
  • •E.O.L.
  • •Pediatric Infuvite Multiple Vitamins
  • •Multi-Vitamin Drops with Fluoride and Iron
  • •Adaptopath
  • •Essential Weight LOSS
  • •Multi-Vitamin with Fluoride
  • •Metabolism
  • •NS Support
  • •Virexa
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.09/gA2B Chem LLC
CountryUnited States
Pack$85.00 / 1 kg
Purity98%
Vendors32 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

31 more vendors
VendorCountry$/gPackPurity
AA BLOCKSUnited States$0.101 kg99%
BLD Pharmatech GmbHGermany$0.111 kg99%
BLD Pharmatech Ltd.China$0.111 kg99%
Aaron Chemicals LLCHong Kong$0.11500 g99.5%
BLD Pharmatech Co., LimitedUnited States$0.121 kg99%
Ambeed, Inc.United States$0.121 kg99%
Angene ChemicalChina → Hong Kong$0.13500 g99.5%
AstaTech, IncUnited States$0.16250 g95%
MedKoo Biosciences, IncUnited States$0.195 kg98%
Sigma-Aldrich (Rush Stock)Germany$0.2110 kg98%
Sigma-AldrichGermany$0.2110 kg98%
Combi-Blocks, Inc.United States$0.251 kg98%
Apollo Scientific USUnited Kingdom$0.291 kg99%
Biopharma PEG Scientific Inc.United States$0.35500 g99%
AK Scientific, Inc.United States$0.42500 g99%
Cayman EuropeEstonia$0.68500 g98%
Fluorochem UKUnited Kingdom$7.151 g95%
TargetMol ChemicalsChina → United States$29.502 g99.96%
AK Scientific SpecializedUnited States$39.001 g99%
TargetMol Chemicals USUnited States$42.001 g99.96%
MolnovaChina$61.001 g99%
MedChemExpress MCESweden$62.921 g99.99%
CliniSciences GmbHSwitzerland$64.50500 mg99%
Angene International LimitedUnited States$96.001 g99%
Labotest KGGermany$217.805000 mg90%
Apexbio Technology LLCUnited States$1000.0050 mg99.99%
ChemFacesChina$1500.0020 mg98%
AngeneChina → Hong Kong$2500.0030 mg99.5%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
Life Chemicals Inc.Ukraine → Canada$3100.00100 mg90%
Key Organics Ltd.United Kingdom$6900.0010 mg99%

Chemical Identity

CAS67-03-8
PubChem CID6202
DTXSIDDTXSID0040622
FormulaC12H18Cl2N4OS
Mol. Weight337.3 g/mol
SMILESCC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.Cl.[Cl-]

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Thiamine hydrochloride (CAS 67-03-8) https://chemicalindependence.com/chemical/67-03-8/ EPA CompTox (DSSTox): DTXSID0040622. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0040622 PubChem: 6202. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6202 EPA Chemical Data Reporting: 67-03-8. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 67-03-8. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293622 for CAS 67-03-8. Reporting year: 2024. https://usatrade.census.gov/