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calcium gluconate monohydrate

Drug ingredient

CAS 66905-23-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 66905-23-5
1 Ca²⁺ · 1 H₂O
US productionNot reported
Import value, 2024$16M
Top sourceItaly 41%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291816 · basket

These shares come from HS customs code 291816, which covers 9 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 41%ItalyCN 32%ChinaIN 17%IndiaDE 6%GermanyTR 2%Turkey
17 FDA-registered drug labelers
Amneal Pharmaceuticals Private Limited
B. Braun Medical Inc.
Fresenius Kabi USA, LLC
Global Calcium Private Limited
Global Calcium Private Limited Unit III
Harman Finochem Limited
Henry Schein, Inc.
HF Acquisition Co LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
HONOUR LAB LIMITED
Medical Purchasing Solutions, LLC
NURAY CHEMICALS PRIVATE LIMITED
Professional Compounding Centers of America dba PCCA
ProPharma Distribution
REMEDYREPACK INC.
Somerset Therapeutics, LLC
WG Critical Care, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Calcium Gluconate
  • •Calcium Gluconate in Sodium Chloride
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS66905-23-5
PubChem CID23724989
DTXSIDDTXSID2047226
FormulaC12H24CaO15
Mol. Weight448.39 g/mol
SMILESC(C(C(C(C(C(=O)[O-])O)O)O)O)O.C(C(C(C(C(C(=O)[O-])O)O)O)O)O.O.[Ca+2]

Data Sources

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Brief citations

calcium gluconate monohydrate (CAS 66905-23-5) https://chemicalindependence.com/chemical/66905-23-5/ PubChem: 23724989. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/23724989 FDA National Drug Code directory: CAS 66905-23-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291816 for CAS 66905-23-5. Reporting year: 2024. https://usatrade.census.gov/