Halobetasol propionate

Drug ingredient

CAS 66852-54-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.1B

Top sourceSingapore 82%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293722 · basket

These shares come from HS customs code 293722, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 82%SingaporeGB 15%United KingdomIT 2%Italy

India
Portugal
China
Mexico
Spain
Malaysia
Canada
Israel
Jordan
Belgium

14 FDA-registered drug labelers

Bausch Health US, LLC

Bryant Ranch Prepack

Coral Way Pharma, LLC

Cosette Pharmaceuticals, Inc.

Hovione FarmaCiencia SA

Lacer Pharma, LLC

Mayne Pharma

Padagis Israel Pharmaceuticals Ltd

QUAGEN PHARMACEUTICALS LLC

Sterling S.p.A.

Symbiotec Pharmalab Limited

Symbiotica Speciality Ingredients Sdn. Bhd.

Trifarma S.p.A.

Wavelength Enterprises LTD

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Halobetasol Propionate
•Duobrii
•Ultravate
•Bryhali
•Lexette

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS66852-54-8

PubChem CID6918178

DTXSIDDTXSID6046636

FormulaC25H31ClF2O5

Mol. Weight485 g/mol

SMILESCCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)CCl

Data Sources

PubChem · compound 6918178Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Halobetasol propionate (CAS 66852-54-8) https://chemicalindependence.com/chemical/66852-54-8/ PubChem: 6918178. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6918178 FDA National Drug Code directory: CAS 66852-54-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293722 for CAS 66852-54-8. Reporting year: 2024. https://usatrade.census.gov/