Bisoprolol

Drug ingredient

CAS 66722-44-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$197M

Top sourceChina 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292219 · basket

These shares come from HS customs code 292219, which covers 167 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 36%ChinaIT 15%ItalyDE 14%GermanyIN 7%IndiaHU 5%Hungary

Saudi Arabia
Lithuania
Canada
Ukraine
Israel
Singapore
Mexico
Ireland
Netherlands
Malaysia
Slovakia
Denmark
Finland
Latvia
Greece
Austria

1 FDA-registered drug labeler

Ipca Laboratories Limited

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$9.00/gAaron Chemicals LLC

CountryHong Kong

Pack$900.00 / 100 g

Purity98%

Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$9.28	25 g	98%
A2B Chem LLC	United States	$15.60	25 g	98%
AA BLOCKS	United States	$20.40	25 g	98%
Combi-Blocks (back-ordered)	United States	$306.00	10 g	95%
AstaTech, Inc	United States	$459.00	1 g	99%
MedChemExpress MCE	Sweden	$474.32	500 mg	99.84%
Apexbio Technology LLC	United States	$500.00	100 mg	99.53%
TargetMol Chemicals	China → United States	$600.00	50 mg	99.95%
AK Scientific, Inc.	United States	$642.00	1 g	98%
Combi-Blocks, Inc.	United States	$840.00	1 g	95%
Angene International Limited	United States	$1020.00	1 g	98%
Molnova	China	$1960.00	25 mg	99%
Angene	China → Hong Kong	$2500.00	30 mg	98%
MedKoo Biosciences, Inc	United States	$2600.00	250 mg	98%
Sigma-Aldrich (Rush Stock)	Germany	$2610.40	200 mg	—
Sigma-Aldrich	Germany	$2610.40	200 mg	—
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
AK Scientific Specialized	United States	$2890.00	100 mg	95%
Key Organics Ltd.	United Kingdom	$8500.00	10 mg	97%

Chemical Identity

CAS66722-44-9

PubChem CID2405

DTXSIDDTXSID6022682

FormulaC18H31NO4

Mol. Weight325.4 g/mol

SMILESCC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O

Data Sources

PubChem · compound 2405Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Bisoprolol (CAS 66722-44-9) https://chemicalindependence.com/chemical/66722-44-9/ PubChem: 2405. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/2405 FDA National Drug Code directory: CAS 66722-44-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292219 for CAS 66722-44-9. Reporting year: 2024. https://usatrade.census.gov/