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Alendronic Acid

Drug ingredient

CAS 66376-36-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 66376-36-1
US productionNot reported
Import value, 2024$598M
Top sourceChina 89%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293149 · basket

These shares come from HS customs code 293149, which covers 114 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 89%ChinaIN 4%IndiaCA 3%CanadaDE 2%GermanyAR 1%Argentina
1 FDA-registered drug labeler
Aesica Pharmaceuticals GmbH, Zwickau

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS66376-36-1
PubChem CID2088
DTXSIDDTXSID5022568
FormulaC4H13NO7P2
Mol. Weight249.1 g/mol
SMILESC(CC(O)(P(=O)(O)O)P(=O)(O)O)CN

Data Sources

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Brief citations

Alendronic Acid (CAS 66376-36-1) https://chemicalindependence.com/chemical/66376-36-1/ PubChem: 2088. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/2088 FDA National Drug Code directory: CAS 66376-36-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293149 for CAS 66376-36-1. Reporting year: 2024. https://usatrade.census.gov/