(2Z)-4-Oxo-5,8,11,14-tetraoxahexacos-2-en-1-oic acid

CAS 66104-67-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$139M

Top sourceChina 67%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291719 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291719, which covers 176 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 67%ChinaCA 13%CanadaAT 4%AustriaIN 4%IndiaJP 4%Japan

Taiwan
Netherlands
Switzerland
Mexico
South Africa
Denmark
Malaysia
Ukraine
Colombia
Hong Kong
Slovakia

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Colonial Chemical

Southern Chemical & Textiles

Why It Matters

Sectors

Consumer ProductsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Intermediate in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing as a reactant
•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
•Surfactant (surface active agent) in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS66104-67-4

PubChem CID6437561

DTXSIDDTXSID1041398

FormulaC22H40O7

Mol. Weight416.5 g/mol

SMILESCCCCCCCCCCCCOCCOCCOCCOC(=O)C=CC(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID1041398Retrieved 2026-04-06
PubChem · compound 6437561Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Consumer Products

Brief citations

(2Z)-4-Oxo-5,8,11,14-tetraoxahexacos-2-en-1-oic acid (CAS 66104-67-4) https://chemicalindependence.com/chemical/66104-67-4/ EPA CompTox (DSSTox): DTXSID1041398. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1041398 PubChem: 6437561. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6437561 EPA Chemical Data Reporting: 66104-67-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 66104-67-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291719 for CAS 66104-67-4. Reporting year: 2024. https://usatrade.census.gov/