1-Docosanol

Drug ingredient

CAS 661-19-8

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$103M

Top sourceGermany 46%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290519 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290519, which covers 122 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 46%GermanyMX 17%MexicoIN 11%IndiaCN 7%ChinaJP 3%Japan

Indonesia
Brazil
Canada
Singapore
Armenia
Slovakia
Argentina
Ukraine
Ireland
Netherlands
Hong Kong

Domestic parents -- activity not disclosed (2)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Nalco- An Ecolab

Snf Holding

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

S.C. Johnson & Son

Sasol Chemicals (Usa)

Why It Matters

Sectors

Core ChemicalsHealthEnergyConsumer ProductsPaints & CoatingsPaper & Printing

Downstream Uses

Appears in 9 drug and cosmetic product listings (FDA).

•iShanCare COLD SORE Treatment
•Cold Sore Fever Blister Treatment
•Docosanol
•Cold Sore Treatment
•Cold Sore Fever Blister
•Julie Cold Sore Treatment
•Cold Sore Treatment Docosanol
•Abreva

Show all 9

•Amazon Basics Docosanol

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 6 sectors as 5 functional roles.

•Dispersing agent in Printing Ink Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
•Emulsifier in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
•Emulsifier in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant
•Stabilizing agent in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Surfactant (surface active agent) in Not Known or Reasonably AscertainableNot Known or Reasonably Ascertainable

Vendor Pricing

$0.09/gAaron Chemicals LLC

CountryHong Kong

Pack$47.00 / 500 g

Purity95%

Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.11	500 g	95%
A2B Chem LLC	United States	$0.13	500 g	95%
AA BLOCKS	United States	$0.14	500 g	98%
BLD Pharmatech GmbH	Germany	$0.15	1 kg	95%
BLD Pharmatech Ltd.	China	$0.15	1 kg	95%
BLD Pharmatech Co., Limited	United States	$0.17	1 kg	95%
Ambeed, Inc.	United States	$0.17	1 kg	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	95%
Angene International Limited	United States	$0.65	500 g	80%
Cayman Europe	Estonia	$0.96	250 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$1.40	50 g	98%
Sigma-Aldrich	Germany	$1.40	50 g	98%
AK Scientific, Inc.	United States	$1.52	100 g	98%
MedChemExpress MCE	Sweden	$16.82	10 g	99.84%
TargetMol Chemicals	China → United States	$34.00	1 g	98.07%
Molnova	China	$74.00	500 mg	99%
Labotest KG	Germany	$217.80	5000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS661-19-8

PubChem CID12620

DTXSIDDTXSID4027286

FormulaC22H46O

Mol. Weight326.6 g/mol

SMILESCCCCCCCCCCCCCCCCCCCCCCO

Data Sources

EPA CompTox (DSSTox) · DTXSID4027286Retrieved 2026-04-06
PubChem · compound 12620Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Core Chemicals

Brief citations

1-Docosanol (CAS 661-19-8) https://chemicalindependence.com/chemical/661-19-8/ EPA CompTox (DSSTox): DTXSID4027286. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4027286 PubChem: 12620. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12620 EPA Chemical Data Reporting: 661-19-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 661-19-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290519 for CAS 661-19-8. Reporting year: 2024. https://usatrade.census.gov/