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Glucosamine hydrochloride

Drug ingredient

CAS 66-84-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 66-84-2
1 HCl
US productionNot reported
Import value, 2024$3.5B
Top sourceIreland 57%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
1 FDA-registered drug labeler
Bispit Canada Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Gout Relief 3310-S
  • •Gout Relief 3310A Plus
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.04/gAaron Chemicals LLC
CountryHong Kong
Pack$18.00 / 500 g
Purity98%
Vendors31 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

30 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.041 kg98%
Apollo Scientific UKUnited Kingdom$0.045 kg98%
A2B Chem LLCUnited States$0.0610 kg98%
AA BLOCKSUnited States$0.0610 kg98%
Ambeed, Inc.United States$0.111 kg98%
AK Scientific SpecializedUnited States$0.20500 g95%
Angene International LimitedUnited States$0.21250 g98%
Combi-Blocks, Inc.United States$0.251 kg97%
AK Scientific, Inc.United States$0.31500 g98%
Cayman EuropeEstonia$0.49500 g95%
AstaTech, IncUnited States$0.8520 g95%
PharmaBlock USUnited States$1.26250 g97%
MedChemExpress MCESweden$1.50100 g98%
BLD Pharmatech Ltd.China$1.581 kg98%
BLD Pharmatech Co., LimitedUnited States$1.58500 g98%
BLD Pharmatech GmbHGermany$1.58500 g98%
Fluorochem EUGermany$1.94100 g97%
Fluorochem UKUnited Kingdom$2.5225 g97%
SynthonixUnited States$3.0010 g98%
ChemsceneUnited States$6.84100 g—
Accela ChemBioUnited States$39.001 g97%
Key Organics Ltd.United Kingdom$75.001 g97%
TargetMol ChemicalsChina → United States$98.001 g99.895%
Sigma-Aldrich (Rush Stock)Germany$104.5425 g99%
Sigma-AldrichGermany$104.5425 g99%
Apexbio Technology LLCUnited States$200.00500 mg98%
Labotest KGGermany$453.001000 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
A2B Chem LLC (1 week)United States$975000.001 mg98%
AA BLOCKS (1 week)United States$1080000.001 mg98%

Chemical Identity

CAS66-84-2
PubChem CID91431
DTXSIDDTXSID5037236
FormulaC6H14ClNO5
Mol. Weight215.63 g/mol
SMILESC(C(C(C(C(C=O)N)O)O)O)O.Cl

Data Sources

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Brief citations

Glucosamine hydrochloride (CAS 66-84-2) https://chemicalindependence.com/chemical/66-84-2/ PubChem: 91431. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/91431 EPA TSCA Inventory: CAS 66-84-2. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293299 for CAS 66-84-2. Reporting year: 2024. https://usatrade.census.gov/