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sitagliptin phosphate

Drug ingredient

CAS 654671-77-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 654671-77-9
1 H₂O
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
34 FDA-registered drug labelers
A-S Medication Solutions
Aesica Queenborough Limited
Alivus Life Sciences Limited
Amoli Organics (A Division of Umedica Laboratories Pvt. Ltd.)
Aurobindo Pharma Limited
Biocon Limited
Cardinal Health 107, LLC
Chromo Laboratories India Private Limited
Dr. Reddy's Laboratories Limited
F.I.S. - Fabbrica Italiana Sintetici S.p.A.
Harman Finochem Limited
HIKAL LIMITED
Honour Lab Limited
IOL Chemicals and Pharmaceuticals Ltd.
Jubilant Biosys limited
Lee Pharma Ltd.
Matrix Pharmacorp Private Limited
Merck Sharp & Dohme LLC
Moehs BCN SL
MSD International GmbH (Singapore Branch)
MSN Life Sciences Private Limited
MSN Pharmachem Private Limited
Organon Heist
ORGANON PHARMA (UK) LIMITED
Patheon Inc.
Patheon Puerto Rico, Inc.
PURE AND CURE HEALTHCARE PRIVATE LIMITED
SMS Pharmaceuticals Limited
Teva API India Private Ltd
Teva Pharmaceuticals USA, Inc.
Union Quimico Farmaceutica SA
Wavelength Enterprises Ltd
Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.
zhejiang jiuzhou pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Januvia
  • •Steglujan
  • •Janumet XR
  • •Janumet
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS654671-77-9
PubChem CID11591741
DTXSIDDTXSID50904746
FormulaC16H20F6N5O6P
Mol. Weight523.32 g/mol
SMILESC1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O

Data Sources

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Brief citations

sitagliptin phosphate (CAS 654671-77-9) https://chemicalindependence.com/chemical/654671-77-9/ PubChem: 11591741. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11591741 FDA National Drug Code directory: CAS 654671-77-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 654671-77-9. Reporting year: 2024. https://usatrade.census.gov/