Isosorbide
Used in 2 industrial sectors tracked by the EPA.
US Production1.2M lbs
Import Value$3.5B
Import Volume80.0K lbs
Import Dependency6%
Top SourceIreland 57%
Where It Comes From
Customs basis: HS 293299 · basket
These shares come from HS customs code 293299, which covers 27 chemicals in total. They estimate the bucket's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2023).
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
- United Kingdom
- Japan
- Germany
- Spain
- Israel
- Canada
- Brazil
- Vietnam
- Ukraine
- New Zealand
- Belgium
- Mexico
- Singapore
- Taiwan
- South Korea
- Sweden
- South Africa
- Egypt
- Indonesia
- Lithuania
- Finland
- Hungary
- Czech Republic
- Hong Kong
- Malaysia
- Slovakia
- Australia
- Russia
- Jordan
- Latvia
- Argentina
- Slovenia
- Malta
- Poland
- Denmark
- Austria
EPA-registered manufacturers (1)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Croda
EPA-registered importers (1)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Roquette America
Why It Matters
Sectors
Plastics & RubberCore Chemicals
Downstream UsesNo data available
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 1 sector as 1 functional role.
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
Chemical Identity
CAS652-67-5
PubChem CID12597
DTXSIDDTXSID5046196
FormulaC6H10O4
Mol. Weight146.14 g/mol
SMILESC1C(C2C(O1)C(CO2)O)O
Data Sources
DTXSID50461962026-04-06
https://doi.org/10.23645/epacomptox.5588566
Archive: data/sources/comptox/dsstox_identifiers.csv
125972026-04-06
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/12597/property/MolecularFormula,MolecularWeight,CanonicalSMILES,InChIKey/JSON
Archive: data/sources/pubchem_properties/12597.json
652-67-52026-04-24
https://www.epa.gov/chemical-data-reporting
Archive: data/sources/epa_cdr/2020_cdr.csv
CAS 652-67-52026-04-25
https://www.epa.gov/chemical-data-reporting
Archive: data/sources/epa_cdr/2020_cdr_industrial.csv