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Yohimbine hydrochloride

CAS 65-19-0

Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, hydrochloride (1:1), (16α,17α)-

Molecular structure of 65-19-0
1 HCl
US productionNot reported
Import value, 2024$171M
Top sourceSwitzerland 40%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India

Why It Matters

No EPA sector or FDA product records name a use for this chemical.

Chemical Identity

CAS65-19-0
PubChem CIDNot recorded
DTXSIDDTXSID40891272
FormulaC21H27ClN2O3
Mol. Weight390.91 g/mol
SMILESCl.[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=C3C=CC=C1)C2

Data Sources

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Brief citations

Yohimbine hydrochloride (CAS 65-19-0) https://chemicalindependence.com/chemical/65-19-0/ EPA TSCA Inventory: CAS 65-19-0. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory US Census international trade: HS 293979 for CAS 65-19-0. Reporting year: 2024. https://usatrade.census.gov/