4-Amino-5-methoxy-2-methylbenzenesulfonic acid

CAS 6471-78-9

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$64M

Top sourceChina 52%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292229 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292229, which covers 84 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 52%ChinaJP 25%JapanIN 18%IndiaIT 3%ItalyKR 1%South Korea

United Kingdom
Ukraine
Canada
Switzerland
Ireland
Netherlands
Israel
Singapore
Latvia
Hong Kong
Belgium

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Sensient Colors

Why It Matters

Sectors

Food

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Dye in Food, beverage, and tobacco product manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.13/gA2B Chem LLC

CountryUnited States

Pack$63.00 / 500 g

Purity97%

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$0.14	500 g	97%
Aaron Chemicals LLC	Hong Kong	$0.17	500 g	97%
BLD Pharmatech Co., Limited	United States	$0.18	500 g	97%
BLD Pharmatech GmbH	Germany	$0.18	500 g	97%
BLD Pharmatech Ltd.	China	$0.18	500 g	97%
Ambeed, Inc.	United States	$0.18	500 g	97%
Angene Chemical	China → Hong Kong	$0.18	500 g	97%
AK Scientific Specialized	United States	$0.22	500 g	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	97%
AK Scientific, Inc.	United States	$0.29	500 g	98%
Angene International Limited	United States	$0.41	500 g	95%
AstaTech, Inc	United States	$17.64	25 g	94%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS6471-78-9

PubChem CID80961

DTXSIDDTXSID2027628

FormulaC8H11NO4S

Mol. Weight217.24 g/mol

SMILESCC1=CC(=C(C=C1S(=O)(=O)O)OC)N

Data Sources

EPA CompTox (DSSTox) · DTXSID2027628Retrieved 2026-04-06
PubChem · compound 80961Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

4-Amino-5-methoxy-2-methylbenzenesulfonic acid (CAS 6471-78-9) https://chemicalindependence.com/chemical/6471-78-9/ EPA CompTox (DSSTox): DTXSID2027628. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2027628 PubChem: 80961. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/80961 EPA Chemical Data Reporting: 6471-78-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 6471-78-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292229 for CAS 6471-78-9. Reporting year: 2024. https://usatrade.census.gov/